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merck millipore,默克密理博,444283,MMP-13 Inhibitor - CAS 544678-85-5 - Calbiochem
产品名称:MMP-13 Inhibitor - CAS 544678-85-5 - Calbiochem
产品型号:444283
The MMP-13 Inhibitor, also referenced under CAS 544678-85-5, controls the biological activity of MMP-13. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
merck millipore,默克密理博,444283,MMP-13 Inhibitor - CAS 544678-85-5 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₂₂H₂₀F₂N₄O₂ 544678-85-5 描述 概述 A pyrimidine dicarboxamide compound that potently inhibits MMP-13 activity (IC50 = 8 nM) with expected selectivity over MMP-1, -2, -3, -7, -8, -9, -10, -12, -14 and -16 as determined by conformational structure analysis. Shown to bind to the MMP-13 catalytic domain and act as a non-zinc-chelating inhibitor. 产品目录编号 444283 品牌系列 Calbiochem®
同义词 Pyrimidine-4,6-dicarboxylic acid, bis-(4-fluoro-3-methyl-benzylamide) 参考 参考 Engel, C.K., et al. 2005. Chem. Biol. 12, 181. 产品信息 CAS号 544678-85-5 具有ATP竞争性 N 形式 Light yellow solid Hill配方 C₂₂H₂₀F₂N₄O₂ 化学配方 C₂₂H₂₀F₂N₄O₂ Molar Mass 410.4 可逆 N 结构配方图像 生物信息 主靶 MMP-13 activity 主靶IC50 8 nM against MMP-13 纯度 ≥98% by HPLC 理化信息 细胞可渗透 N 溶解度 DMSO 储存和货运信息 货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
毒性 Standard Handling
储存 +2°C to +8°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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