• merck millipore,默克密理博,217720,Cdk1/5 Inhibitor - CAS 40254-90-8 - Calbiochem
  • merck millipore,默克密理博,217720,Cdk1/5 Inhibitor - CAS 40254-90-8 - Calbiochem

    产品名称:Cdk1/5 Inhibitor - CAS 40254-90-8 - Calbiochem
    产品型号:217720
    The Cdk1/5 Inhibitor, also referenced under CAS 40254-90-8, controls the biological activity of Cdk1/5. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applicat More>>

    merck millipore,默克密理博,217720,Cdk1/5 Inhibitor - CAS 40254-90-8 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,217720,Cdk1/5 Inhibitor - CAS 40254-90-8 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₉H₇N₅40254-90-8
    描述
    概述 A 3-amino substituted pyrazoloquinoxaline compound that acts as a selective inhibitor of cyclin-dependent kinases 1 and 5 (Cdks; IC50 = 0.6 µM and 0.4 µM for Cdk1/cyclin B and Cdk5/p25, respectively). Also shown to inhibit GSK-3β with (IC50 = 1 µM). Does not inhibit Cdc25 phosphatase activity (IC50 > 10 µM).
    产品目录编号 217720
    品牌系列 Calbiochem®
    同义词 3-Amino-1H-pyrazolo[3,4-b]quinoxaline
    参考
    参考 Ortega, M.A., et al. 2002. Bioorg. Med. Chem. 10, 2177.
    产品信息
    CAS号 40254-90-8
    具有ATP竞争性 N
    形式 Red solid
    Hill配方 C₉H₇N₅
    化学配方 C₉H₇N₅
    Molar Mass 185.2
    可逆 N
    结构配方图像
    生物信息
    主靶 Cdk1/cyclin B, Cdk5/p25
    主靶IC50 0.6 µM and 0.4 µM for Cdk1/cyclin B and Cdk5/p25, respectively
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,217720,Cdk1/5 Inhibitor - CAS 40254-90-8 - Calbiochem

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