• merck millipore,默克密理博,215901,Carbonic Anhydrase IX/XII Inhibitor II, U-104 - Calbiochem
  • merck millipore,默克密理博,215901,Carbonic Anhydrase IX/XII Inhibitor II, U-104 - Calbiochem

    产品名称:Carbonic Anhydrase IX/XII Inhibitor II, U-104 - Calbiochem
    产品型号:215901
    The Carbonic Anhydrase IX/XII Inhibitr II, U-104 controls the biological activity of Carbonic Anhydrase IX/XII. This small molecule/inhibitor is primarily used for Cancer applications.

    merck millipore,默克密理博,215901,Carbonic Anhydrase IX/XII Inhibitor II, U-104 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,215901,Carbonic Anhydrase IX/XII Inhibitor II, U-104 - Calbiochem

    重要规格表

    经验配方
    C₁₃H₁₂FN₃O₃S
    描述
    概述 A cell permeable ureido-sulfonamide Carbonic Anhydrase (CA) inhibitor that is selective for human hCA IX and hCA XII (Ki = 45 nM and 4.5 nM, respectively) against two other physiologically relevant hCA isoforms (Ki = 5080 nM and 9640 nM for hCA I and hCA II, respectively). It elicits anti-tumor growth effects dose-dependently from 19 to 38 mg/kg in a mouse tumor growth model implanted with MDA-MB-231 LM2-4Luc+ cells, and demonstrates metastasis inhibition in a mouse metastasis model injected with 4T1 cells.
    产品目录编号 215901
    品牌系列 Calbiochem®
    同义词 CAIX Inhibitor II
    参考
    参考 Lock, F.E., et al. 2012. Oncogene in press.
    Pacchiano, F., et al. 2011. J Med Chem. 54, 1896.
    产品信息
    形式 White solid
    Hill配方 C₁₃H₁₂FN₃O₃S
    化学配方 C₁₃H₁₂FN₃O₃S
    Molar Mass 309.3
    结构配方图像
    生物信息
    纯度 ≥98% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Regulatory Review
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,215901,Carbonic Anhydrase IX/XII Inhibitor II, U-104 - Calbiochem

上一件merck millipore产品:merck millipore,默克密理博,05-897,Anti-HDAC9 Antibody, clone LH/JC2
下一件merck millipore产品:merck millipore,默克密理博,ST1551,Anti-GGT1 Mouse mAb (1F9)



whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部