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merck millipore,默克密理博,203390,(±)-Blebbistatin - CAS 674289-55-5 - Calbiochem
产品名称：(±)-Blebbistatin - CAS 674289-55-5 - Calbiochem
产品型号：203390
A cell-permeable compound that acts as a selective, potent, and reversible inhibitor of nonmuscle myosin II.
merck millipore,默克密理博,203390,(±)-Blebbistatin - CAS 674289-55-5 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₁₈H₁₆N₂O₂ 674289-55-5 描述 概述 A cell-permeable compound that acts as a selective, potent, and reversible inhibitor of nonmuscle myosin II. Inhibits the ATPase and gliding motility of human platelets (≤ 100 µM) without affecting myosin light chain kinase (MLCK) activity. Has been shown to block cell blebbing and to rapidly disrupt directed cell migration and cytokinesis in vertebrate cells. Does not disrupt mitosis or affect contractile ring assembly. A 50 mM (5 mg/342 µl) solution of (±)-Blebbistatin (Cat. No. 203389) in 90% DMSO is also available. 产品目录编号 203390 品牌系列 Calbiochem®
参考 参考 Shu, S., et al. 2005. Proc. Natl. Acad. Sci. USA 102, 1472.
Kovacs, M., et al. 2004. J. Biol. Chem. 279, 35557.
Straight, A.F., et al. 2003. Science 299, 1743.
Cheung, A., et al. 2001. Mol. Biol. Cell Suppl. 12, 271a.产品信息 CAS号 674289-55-5 具有ATP竞争性 N 形式 Yellow solid Hill配方 C₁₈H₁₆N₂O₂ 化学配方 C₁₈H₁₆N₂O₂ Molar Mass 292.3 可逆 Y 结构配方图像 生物信息 主靶 ATPase 主靶IC50 <100 µM inhibiting the ATPase and gliding motility of human platelets 纯度 ≥97% by HPLC 理化信息 细胞可渗透 Y 溶解度 DMSO or MeOH 储存和货运信息 货运代码 Blue Ice Only
毒性 Harmful & Carcinogenic / Teratogenic
储存 -20°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution in 90% DMSO, aliquot and freeze (-20°C). Stock solutions in 90% DMSO are stable for up to 1 month at -20°C. Stock solutions in 100% DMSO are unstable; reconstitute just prior to use. 包装信息 惰性气体下包装 Packaged under inert gas
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