merck millipore,默克密理愽
  • merck millipore,默克密理博,172060,Andrographolide - CAS 5508-58-7 - Calbiochem

  • merck millipore,默克密理博,172060,Andrographolide - CAS 5508-58-7 - Calbiochem

    产品名称：Andrographolide - CAS 5508-58-7 - Calbiochem
    产品型号：172060
    A bicyclic diterpenoid lactone that displays anti-viral, anti-inflammatory, anti-apoptotic, and anti-hyperglycemic properties.

    merck millipore,默克密理博,172060,Andrographolide - CAS 5508-58-7 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,172060,Andrographolide - CAS 5508-58-7 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₀H₃₀O₅5508-58-7
    描述
    概述 A bicyclic diterpenoid lactone that displays anti-viral, anti-inflammatory, anti-apoptotic, and anti-hyperglycemic properties. Acts as an irreversible antagonist of NF-κB and AP-1 (IC50 ≤ 15 µM) activation, and prevents in vitro and in vivo T cell activation. Exerts no effect on IκBα degradation, p50 and p65 nuclear translocation. Inhibits iNOS and Mac-1 expressions and ROS production, and prevents endotoxin shock in mouse model. Further, reported to activate PI 3K/Akt pathway.
    产品目录编号 172060
    品牌系列 Calbiochem®
    同义词 Andro
    参考
    参考 Xia, Y.F., et al. 2004. J. Immunol. 173, 4207.
    Chen, J.H., et al. 2004. Biochem. Pharmacol. 67, 1337.
    Yu, B.C., et al. 2003. Planta Med. 69, 1075.
    产品信息
    CAS号 5508-58-7
    具有ATP竞争性 N
    形式 Off-white solid
    Hill配方 C₂₀H₃₀O₅
    化学配方 C₂₀H₃₀O₅
    Molar Mass 350.5
    可逆 N
    结构配方图像
    生物信息
    主靶 NF-κB and AP-1 activation
    主靶IC50 ≤ 15 µM against NF-κB and AP-1 activation
    纯度 ≥95% by TLC
    理化信息
    细胞可渗透 N
    溶解度 DMSO
    GHS安全信息
    RTECS LU3490750
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Carcinogenic / Teratogenic
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,172060,Andrographolide - CAS 5508-58-7 - Calbiochem

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