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merck millipore,默克密理博,17-499,Phosphorylation Explorer Pack Sample Kit
产品名称：Phosphorylation Explorer Pack Sample Kit
产品型号：17-499
This Antibody pack contains Anti-phosphotyrosine Antibody, Anti-Phosphoserine Antibody, validated for use in WB, IF, Flow, IHC, ELISA, ICC.
merck millipore,默克密理博,17-499,Phosphorylation Explorer Pack Sample Kit
- 产品介绍
描述 产品目录编号 17-499 品牌系列 Upstate
商名 - Upstate
描述 Phosphorylation Explorer Pack Sample Kit 背景信息 4G10® Platinum
The development of the anti-phosphotyrosine, clone 4G10® in 1989 was a monumental discovery for researchers. 4G10® was the first and is the best single monoclonal antibody for the detection tyrosine phosphorylation. 4G10® is well known for its sensitivity and its ability to detect multiple tyrosine phosphorylations on numerous substrates. It has been validated by thousands of scientific and medical researchers in virtually every application and tyrosine target over the past 2 decades. To improve on something that hundred have tried and no one has succeeded, we pooled 4G10® with the next most highly regarded anti-phosphotyrosine, clone PY20 to make 4G10® Platinum. PY20 itself is a very poor substitute for 4G10®, but its additive effect allow for a greater level of detection on more substrates that even 4G10® alone was not capable of.
4A4
The identification of protein phosphorylation as a regulatory mechanism originated from studies by Fischer and Krebs in the mid 1950s that later earned them the 1992 Nobel prize. It is the major mechanism for the regulation of diverse cellular processes including cell division, protein synthesis, transcriptional regulation and neurotransmission. The steady state phosphorylation of any given substrate is governed by the opposing activities of kinases and phosphatases. It is now believed that a third of all eukaryotic cellular proteins are phosphorylated and that the majority of all phosphorylation events occur on serine and threonine residues (greater than 95%).产品信息 部件 - This product contains the following components:
- Cat. # 05-1050X 4G10® Platinum, Anti-phosphotyrosine
- Cat. # 05-1000X Anti-Phosphoserine, Clone 4A4
应用 应用 This Antibody pack contains Anti-phosphotyrosine Antibody, Anti-Phosphoserine Antibody, validated for use in WB, IF, Flow, IHC, ELISA, ICC. 主要应用 - Immunocytochemistry
- Western Blotting
- Flow Cytometry
- Immunohistochemistry
- ELISA
生物信息 克隆 4G10® Platinum and 4A4 宿主 Mouse 修改 - Phosphorylation
产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 See individual components for storage/handling conditions. 包装信息 数量 1 kit
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