merck millipore,默克密理愽
  • merck millipore,默克密理博,14-920,CLK1, active

  • merck millipore,默克密理博,14-920,CLK1, active

    产品名称：CLK1, active
    产品型号：14-920


    merck millipore,默克密理博,14-920,CLK1, active

  • 产品介绍
  • merck millipore,默克密理博,14-920,CLK1, active

    描述
    产品目录编号 14-920
    商名
    • Upstate
    描述 CLK1, active
    概述 CLK1 is a dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates: SRSF1, SRSF3 and PTPN1. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells and adenovirus E1A pre-mRNA.
    产品信息
    演示 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol
    应用
    主要应用
    • Kinase Assay
    生物信息
    来源 N-terminal 6His-tagged, recombinant, human CLK1, amino acids 130-end expressed by baculovirus in Sf21 insect cells
    品种 Human
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
    Entrez基因编号
    • NM_004071
    基因符号
    • STY
    • CLK1
    • CLK
    纯化方法 Purified using immobilized metal affinity chromatography.
    靶子系列 CMGC
    UniProt编号
    • P49759
    产品使用声明
    质量保证 Routinely evaluated by phosphorylation of peptide ERMRPRKRQGSVRRRV
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 6 months at -70°C
    包装信息
    数量 10 µg
    包装 Also available in 250μg size as catalog # 14-920M and in bulk as catalog # 14-920-K.

    merck millipore,默克密理博,14-920,CLK1, active

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