merck millipore,默克密理博,260964,Deoxyribonucleic Acid, Sodium Salt, Salmon Testes - CAS 9007-49-2

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Merck Millipore 默克密理愽

merck millipore,默克密理博,260964,Deoxyribonucleic Acid, Sodium Salt, Salmon Testes - CAS 9007-49-2 - Calbiochem

经验配方	CAS号
C₁₇H₁₇NO₃	404009-46-7

描述
概述	A morpholino-benzophenone compound that acts as a potent, selective, reversible, and ATP-competitive inhibitor of DNA-PK (IC₅₀ = 270 nM). Inhibits PI 3-K catalytic subunit p110-isozymes at higher concentrations (IC₅₀ = 32 µM, 3.7 µM, 22 µM and ~ 100 µM for α, β, δ and γ, respectively) and weakly inhibits a panel of several other kinases, including, ATM, ATR, CK2, GRK2, mTOR, PI 3KC2α, PI 3KC2β, PI 3KC2γ and PI 4Kβ, even at concentrations as high as 50 µM.
产品目录编号	260964
品牌系列	Calbiochem®
同义词	AMA37, ArylMorpholine Analog 37, 1-(2-Hydroxy-4-morpholin-4-yl-phenyl)-phenyl-methanone

参考
参考	Knight, Z.A., et al. 2004. Bioorg. Med. Chem. 12, 4749. Willmore, E., et al. 2004. Blood,103, 4659.

理化信息
细胞可渗透	N
溶解度	DMSO

储存和货运信息
货运代码	Ambient Temperature Only
毒性	Carcinogenic / Teratogenic
储存	+2°C to +8°C
避光	Protect from light
无需冷冻	No
特殊指南	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

包装信息
惰性气体下包装	Packaged under inert gas

merck millipore,默克密理博,260964,Deoxyribonucleic Acid, Sodium Salt, Salmon Testes - CAS 9007-49-2 - Calbiochem

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