• merck millipore,默克密理博,MABE365,Anti-acetyl PARP1 Antibody, clone E4
  • merck millipore,默克密理博,MABE365,Anti-acetyl PARP1 Antibody, clone E4

    产品名称:Anti-acetyl PARP1 Antibody, clone E4
    产品型号:MABE365
    Anti-acetyl PARP1 Antibody, clone E4 is a highly specific mouse monoclonal antibody & that targets PARP & has been tested in western blotting.

    merck millipore,默克密理博,MABE365,Anti-acetyl PARP1 Antibody, clone E4

  • 产品介绍
  • merck millipore,默克密理博,MABE365,Anti-acetyl PARP1 Antibody, clone E4

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HWBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABE365
    描述 Anti-acetyl PARP1 Antibody, clone E4
    Alternate Names
    • PARP-1
    • ADP-ribosyltransferase diphtheria toxin-like 1
    • ARTD1
    • NAD(+) ADP-ribosyltransferase 1
    • ADPRT 1
    • Poly[ADP-ribose] synthase 1
    • Poly [ADP-ribose] polymerase 1
    背景信息 Poly (ADP-ribose) polymerase 1 (PARP1) is zinc-dependent DNA binding protein that recognizes DNA strand breaks and is presumed to play a role in DNA repair. As a marker for apoptosis, PARP is cleaved in vitro by many caspases and in vivo by Caspase-3. Acetylation of PARP1 by p300/CREB-binding protein is important in the regulation of NF-kappaB-dependent gene activation through enhanced functional interactions with p300 and the Mediator complex.
    产品信息
    格式 Purified
    控制
    • Acetylated PARP1 fragment (373-529) purified protein lysate
    演示 Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Anti-acetyl PARP1 Antibody, clone E4 is a highly specific mouse monoclonal antibody & that targets PARP & has been tested in western blotting.
    主要应用
    • Western Blotting
    应用说明 Western Blotting Analysis: 0.5 µg/mL from a representative lot detected wild type acetyl-PARP 1, but did not react with four acetylation-deficient PARP1 KQR mutants in WB (Messner, S., et al. (2009). The FASEB Journal. 23:3978-3989).
    生物信息
    免疫原品种 Linear peptide corresponding to acetylated human PARP1, short fragment.
    克隆 E4
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    同种型 IgG2bκ
    品种反应性 Human
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_001609
    基因符号
    • ARTD1
    • PARP1
    • ADPRT
    • PPOL
    • PARP
    纯化方法 Protein G purified
    UniProt编号
    • P09874
    产品使用声明
    质量保证 Evaluated by Western Blotting in acetylated PARP1 fragment (373-529) purified protein lysate.

    Western Blotting Analysis: 0.5 µg/mL of this antibody detected acetyl PARP1 in 10 µg of acetylated PARP1 fragment (373-529) purified protein lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MABE365,Anti-acetyl PARP1 Antibody, clone E4

上一件merck millipore产品:merck millipore,默克密理博,260964,Deoxyribonucleic Acid, Sodium Salt, Salmon Testes - CAS 9007-49-2 - Calbiochem
下一件merck millipore产品:merck millipore,默克密理博,100069,17-DMAG - CAS 467214-21-7 - Calbiochem



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