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merck millipore,默克密理博,MABE365,Anti-acetyl PARP1 Antibody, clone E4
产品名称:Anti-acetyl PARP1 Antibody, clone E4
产品型号:MABE365
Anti-acetyl PARP1 Antibody, clone E4 is a highly specific mouse monoclonal antibody & that targets PARP & has been tested in western blotting.
merck millipore,默克密理博,MABE365,Anti-acetyl PARP1 Antibody, clone E4
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB M Purified Monoclonal Antibody 描述 产品目录编号 MABE365 描述 Anti-acetyl PARP1 Antibody, clone E4 Alternate Names - PARP-1
- ADP-ribosyltransferase diphtheria toxin-like 1
- ARTD1
- NAD(+) ADP-ribosyltransferase 1
- ADPRT 1
- Poly[ADP-ribose] synthase 1
- Poly [ADP-ribose] polymerase 1
背景信息 Poly (ADP-ribose) polymerase 1 (PARP1) is zinc-dependent DNA binding protein that recognizes DNA strand breaks and is presumed to play a role in DNA repair. As a marker for apoptosis, PARP is cleaved in vitro by many caspases and in vivo by Caspase-3. Acetylation of PARP1 by p300/CREB-binding protein is important in the regulation of NF-kappaB-dependent gene activation through enhanced functional interactions with p300 and the Mediator complex. 产品信息 格式 Purified 控制 - Acetylated PARP1 fragment (373-529) purified protein lysate
演示 Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-acetyl PARP1 Antibody, clone E4 is a highly specific mouse monoclonal antibody & that targets PARP & has been tested in western blotting. 主要应用 - Western Blotting
应用说明 Western Blotting Analysis: 0.5 µg/mL from a representative lot detected wild type acetyl-PARP 1, but did not react with four acetylation-deficient PARP1 KQR mutants in WB (Messner, S., et al. (2009). The FASEB Journal. 23:3978-3989). 生物信息 免疫原品种 Linear peptide corresponding to acetylated human PARP1, short fragment. 克隆 E4 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgG2bκ 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_001609
基因符号 - ARTD1
- PARP1
- ADPRT
- PPOL
- PARP
纯化方法 Protein G purified UniProt编号 - P09874
产品使用声明 质量保证 Evaluated by Western Blotting in acetylated PARP1 fragment (373-529) purified protein lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected acetyl PARP1 in 10 µg of acetylated PARP1 fragment (373-529) purified protein lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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