merck millipore,默克密理博,SF-778,MAP1LC3B; Human, Cyanine 3, RNA Detection Probe,SmartFlare

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Merck Millipore 默克密理愽

Entrez Gene Number	Species Reactivity
NM_022818.4	H

描述
产品目录编号	SF-778
商名	SmartFlare
描述	MAP1LC3B; Human, Cyanine 3, RNA Detection Probe \| SmartFlare
Alternate Names	MAP1LC3B-a LC3B ATG8F
背景信息	With SmartFlare™ RNA Detection probes, you can detect RNA in LIVE CELLS with ease. With just an overnight incubation of MAP1LC3B; Human, Cyanine 3, RNA Detection Probe you can detect the presence of MAP1LC3B within your cells. Microtubule-associated MAPILC3A constitute nearly half of the mass of all the microtubule associated proteins that copurify with brain microtubules. MAPILC3A is composed of a heavy chain and multiple light-chain subunits. Amino acid sequencing of a 120 kd microtubule-binding and light chain-binding fragment of the heavy chain reveals that light chain 1 binds near the heavy chain N-terminus. These data indicate that the heavy chain and light chain 1 are produced by proteolytic processing of a MAP1B polyprotein and form a complex microtubule-binding domain. There are three human orthologs of the rat Map1LC3, named MAP1LC3A, MAP1LC3B, and MAP1LC3C. The three isoforms of human MAP1LC3 exhibit distinct expression patterns in different human tissues and also differ in their post-translation modifications. MAP1LC3A and MAP1LC3C are produced by the proteolytic cleavage after the conserved C-terminal Gly residue; MAP1LC3B does not undergo C-terminal cleavage and exists in a single modified form.

产品信息
格式	Cyanine 3
演示	Lyophilized

应用
应用	Use SmartFlare RNA Detection probes to measure gene expression in live cells. With an overnight incubation of SmartFlare MAP1LC3B, Human, Cyanine 3, you can detect MAP1LC3B RNA levels within your cells.
主要应用	RNA Detection

产品使用声明
质量保证	SmartFlare Probes have been tested in a buffer system to detect the release of the fluorophore in the presence of a complimentary base pair sequence for each lot to confirm target specificity. SmartFlare Probes have also been tested in a cell model system and demonstrated increased fluorescence in cells expressing the target compared to a negative SmartFlare Scramble Control.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Store at 2–8°C in lyophilized format ONLY. Room temperature is required for reconstituted product.

包装信息
数量	250 reactions

merck millipore,默克密理博,SF-778,MAP1LC3B; Human, Cyanine 3, RNA Detection Probe,SmartFlare

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