merck millipore,默克密理愽
  • merck millipore,默克密理博,04-539,Anti-MAPKAP-K2 Antibody, clone 7H4.2

  • merck millipore,默克密理博,04-539,Anti-MAPKAP-K2 Antibody, clone 7H4.2

    产品名称：Anti-MAPKAP-K2 Antibody, clone 7H4.2
    产品型号：04-539
    Anti-MAPKAP-K2 Antibody, clone 7H4.2 detects level of MAPKAP-K2 & has been published & validated for use in IP & WB.

    merck millipore,默克密理博,04-539,Anti-MAPKAP-K2 Antibody, clone 7H4.2

  • 产品介绍
  • merck millipore,默克密理博,04-539,Anti-MAPKAP-K2 Antibody, clone 7H4.2

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, H, MWBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 04-539
    品牌系列 Upstate
    商名
    • Upstate
    描述 Anti-MAPKAP-K2 Antibody, clone 7H4.2
    Alternate Names
    • MAPK-activated protein kinase 2, MAPKAP kinase 2
    • MAPK-activated protein kinase 2
    产品信息
    格式 Purified
    演示 200 µg (1 mg/mL) of mouse monoclonal IgG in PBS containing 0.1% sodium azide.
    应用
    应用 Anti-MAPKAP-K2 Antibody, clone 7H4.2 detects level of MAPKAP-K2 & has been published & validated for use in IP & WB.
    主要应用
    • Western Blotting
    应用说明 Suggested dilutions:
    Immunoblot Analysis: 1:500
    Immunoprecipitation: 1:20
    生物信息
    免疫原品种 KLH-conjugated synthetic peptide of the C-terminus of the long form of human MAPKAP-K2.
    克隆 7H4.2
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    同种型 IgG
    品种反应性 RatHumanMouse
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_032960.2
    • NM_004759.3
    Entrez基因汇总 This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.
    基因符号
    • MAPKAPK-2
    • MAPKAPK2
    • MK2
    纯化方法 Protein A purfied
    UniProt编号
    • P49137
    UniProt汇总 FUNCTION: SwissProt: P49137 # Its physiological substrate seems to be the small heat shock protein (HSP27/HSP25). In vitro can phosphorylate glycogen synthase at 'Ser-7' and tyrosine hydroxylase (on 'Ser-19' and 'Ser-40'). This kinase phosphorylates Ser in the peptide sequence, Hyd-X-R-X(2)-S, where Hyd is a large hydrophobic residue (By similarity). Mediates both ERK and p38 MAPK/MAPK14 dependent neutrophil responses. Participates in TNF alpha-stimulated exocytosis of secretory vesicles in neutrophils. Plays a role in phagocytosis-induced respiratory burst activity.
    SIZE: 400 amino acids; 45568 Da
    SUBUNIT: Interacts with PHC2.
    TISSUE SPECIFICITY: Expressed in all tissues examined.
    PTM: Phosphorylated and activated by MAP kinase.
    SIMILARITY: SwissProt: P49137 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 protein kinase domain.
    产品使用声明
    质量保证 Routinely evaluated by immunoblot.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 2 years at -20°C from date of shipment.
    包装信息
    数量 200 µg

    merck millipore,默克密理博,04-539,Anti-MAPKAP-K2 Antibody, clone 7H4.2

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