merck millipore,默克密理博,14-843,Hck Protein, activated, 10 µg

搜索"Merck Millipore 密理愽"产品

Merck Millipore 默克密理愽

当前位置：首页 > >Merck Millipore > 生命科学研究
生命科学研究

merck millipore,默克密理博,14-843,Hck Protein, activated, 10 µg
产品名称：Hck Protein, activated, 10 µg
产品型号：14-843
activated, N-terminal 6His-tagged, recombinant, human Hck, amino acids 230–497, for use in Kinase Assays.

merck millipore,默克密理博,14-843,Hck Protein, activated, 10 µg

产品介绍

merck millipore,默克密理博,14-843,Hck Protein, activated, 10 µg

描述
产品目录编号	14-843
品牌系列	Upstate
商名	Upstate
描述	Hck Protein, activated, 10 µg
概述	N-terminal 6His-tagged, recombinant, human Hck, amino acids 230–497

产品信息
演示	50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol, 5mM β-glycerophosphate, 1mM Na3VO4. Frozen solution.

应用
应用	activated, N-terminal 6His-tagged, recombinant, human Hck, amino acids 230–497, for use in Kinase Assays.
主要应用	Kinase Assay
应用说明	Auto-activated on column by incubating with Mg/ATP, excess ATP and MgAc removed by multiple column wash steps.

生物信息
来源	Expressed by baculovirus in Sf21 insect cells
品种	Human
特异活性	For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez基因编号	NM_002110.2
Entrez基因汇总	The protein encoded by this gene is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types. The encoded protein may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization.
基因符号	JTK9 HCK p59-HCK/p60-HCK
蛋白靶	Hck
纯化方法	Ni²⁺/NTA-agarose
靶子系列	TK
UniProt编号	P08631
UniProt汇总	FUNCTION: SwissProt: P08631 # May serve as part of a signaling pathway coupling the Fc receptor to the activation of the respiratory burst. May also contribute to neutrophil migration and may regulate the degranulation process of neutrophils. SIZE: 526 amino acids; 59600 Da SUBUNIT: May bind to HIV-1 Nef and VIF through its SH3 domain. This interaction would stimulates its tyrosine-kinase activity. SUBCELLULAR LOCATION: Isoform p59-HCK: Membrane; Lipid-anchor. & Isoform p60-HCK: Membrane; Lipid-anchor. Cytoplasm. TISSUE SPECIFICITY: Expressed predominantly in cells of the myeloid and B-lymphoid lineages. DOMAIN: SwissProt: P08631 The SH3 domain mediates binding to HIV-1 Nef. PTM: Isoform p59-HCK contains a N-myristoyl glycine at position 3 (By similarity). Isoform p59-HCK contains a S-palmitoyl cysteine at position 3 (By similarity). SIMILARITY: Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily. & Contains 1 protein kinase domain. & Contains 1 SH2 domain. & Contains 1 SH3 domain.

产品使用声明
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	6 months at -70°C

包装信息
数量	10 µg
包装	Also available in 250 µg size --call for pricing and availability and reference catalog number 14-843M when ordering the 250 µg size.

merck millipore,默克密理博,14-843,Hck Protein, activated, 10 µg

上一件merck millipore产品：merck millipore,默克密理博,565852,PTP Inhibitor XXXI, II-B08 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,AB19021,Anti-α-Catenin Antibody

whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech