merck millipore,默克密理愽
  • merck millipore,默克密理博,14-731M,CaM Kinase Iδ Protein, active, 250 µg

  • merck millipore,默克密理博,14-731M,CaM Kinase Iδ Protein, active, 250 µg

    产品名称：CaM Kinase Iδ Protein, active, 250 µg
    产品型号：14-731M
    Active, N-terminal 6His-tagged, recombinant, human, full length CaM Kinase Iδ. For use in Enzyme Assays.

    merck millipore,默克密理博,14-731M,CaM Kinase Iδ Protein, active, 250 µg

  • 产品介绍
  • merck millipore,默克密理博,14-731M,CaM Kinase Iδ Protein, active, 250 µg

    描述
    产品目录编号 14-731M
    品牌系列 Upstate
    商名
    • Upstate
    描述 CaM Kinase Iδ Protein, active, 250 µg
    概述 N-terminal 6His-tagged, recombinant, human, full length CaM Kinase Iδ.
    Alternate Names
    • CaMKI-delta
    • Calcium/calmodulin-dependent protein kinase type 1D
    产品信息
    演示 Presented as a frozen liquid in 50mM Tris-HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol.
    应用
    应用 Active, N-terminal 6His-tagged, recombinant, human, full length CaM Kinase Iδ. For use in Enzyme Assays.
    主要应用
    • Enzyme Assay
    生物信息
    浓缩 For concentration, please refer to the Certificate of Analysis for individual lots of this enzyme.
    纯度 For purity information, please refer to the Certificate of Analysis for individual lots of this enzyme.
    来源 Recombinant human protein expressed by baculovirus in Sf21 cells.
    品种 Human
    特异活性 For Specific Activity data, please refer to the Certificate of Analysis for individual lots of this enzyme.
    Entrez基因编号
    • NM_153498.2
    • NM_020397.2
    Entrez基因汇总 This gene encodes a member of the Ca2+/calmodulin-dependent protein kinase 1 subfamily of serine/threonine kinases. The encoded protein may be involved in the regulation of granulocyte function through the chemokine signal transduction pathway. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
    基因符号
    • CaMKID
    • CAMK1D
    • CaM-K1
    • CaMKI-delta
    • Camk1D
    • CKLiK
    • OTTHUMP00000045030
    蛋白靶 CaMKIδ
    纯化方法 Ni2+/NTA-agarose
    靶子系列 CAMK
    UniProt编号
    • Q8IU85
    UniProt汇总 FUNCTION: SwissProt: Q8IU85 # Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. May regulate calcium-mediated granulocyte function. May play a role in apoptosis of erythroleukemia cells. Activates MAP kinase MAPK3 (By similarity). In vitro, phosphorylates transcription factor CREM isoform Beta and probably CREB1.
    SIZE: 385 amino acids; 42914 Da
    SUBCELLULAR LOCATION: Cytoplasm (Probable). Nucleus (Probable). Note=Predominantly cytoplasmic (Probable). Also nuclear upon activation (Probable).
    TISSUE SPECIFICITY: Broadly expressed. Highly and mostly expressed in polymorphonuclear leukocytes (neutrophilic and eosinophilic granulocytes) while little or no expression is observed in monocytes and lymphocytes.
    DOMAIN:SwissProt: Q8IU85 The autoinhibitory domain overlaps with the calmodulin binding region and interacts in the inactive folded state with the catalytic domain as a pseudosubstrate (By similarity).
    SIMILARITY: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily. & Contains 1 protein kinase domain.
    产品使用声明
    质量保证 Routinely evaluated by phosphorylation of 150μM KKLRRTLSVA.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 6 months at -70°C from date of shipment. Upon first use, rapidly thaw the vial under cold water and immediately place on ice. Aliquot unused material into pre-chilled microcentrifuge tubes and immediately snap-freeze the vials in liquid nitrogen prior to re-storage at -70deg;C.
    包装信息
    数量 250 µg
    包装 Also available in 20 μg size (cat#14-731) and in bulk (cat# 14-731-K).

    merck millipore,默克密理博,14-731M,CaM Kinase Iδ Protein, active, 250 µg

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