- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
描述 产品目录编号 14-574 品牌系列 Upstate
商名 - Upstate
描述 EphA4 Protein, active, 10 µg 概述 N-terminal His6-tagged recombinant human EphA4 residues 601-892 应用 应用 Active, N-terminal His6-tagged recombinant human EphA4 residues 601-892, for use in Kinase Assays. 主要应用 - Kinase Assay
生物信息 来源 Expressed by baculovirus in Sf21 insect cells 品种 Human 特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. Entrez基因编号 - NM_004438.3
Entrez基因汇总 This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. 基因符号 - SEK
- EPHA4
- Hek8
- HEK8
- EphA4
- TYRO1
蛋白靶 EphA4 纯化方法 Ni2+/NTA-agarose 靶子系列 TK UniProt编号 - P54764
UniProt汇总 FUNCTION: SwissProt: P54764 # Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A4 and -A5. Binds more poorly to ephrin-A2 and -A3. May play a role in a signal transduction process involved in hindbrain pattern formation.
SIZE: 986 amino acids; 109860 Da
SUBUNIT: Interacts with the src family kinase, p59-Fyn, through the major phosphorylation site at position Tyr-602. Interacts with NGEF/ephexin-1 (By similarity).
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
TISSUE SPECIFICITY: Ubiquitous.
DOMAIN: SwissProt: P54764 The protein kinase domain mediates interaction with NGEF/ephexin-1 (By similarity).
SIMILARITY: Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. & Contains 2 fibronectin type-III domains. & Contains 1 protein kinase domain. & Contains 1 SAM (sterile alpha motif) domain.产品使用声明 质量保证 Routinely evaluated by phosphorylation of Poly (Glu4-Tyr) (4:1) 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 6 months at -70°C 包装信息 数量 10 µg 包装 Also available in 250 µg size --call for pricing and availability and reference catalog number 14-574M when ordering the 250 µg size.
上一件merck millipore产品：merck millipore,默克密理博,05-449,Anti-Bin1 Antibody, clone 99D
下一件merck millipore产品：merck millipore,默克密理博,371751,Anti-Gqα- and G₁₁α-Subunits, C-Terminal Rabbit pAb
相关产品
merck millipore,默克密理博,04-1091,Anti-Sir2/SIRT1 Antibody, clone E104, rabbit monoclonal
merck millipore,默克密理博,AB9410,Anti-Adrenoceptor β-2 Antibody
merck millipore,默克密理博,AG105,Black Gold II Myelin Staining Kit
merck millipore,默克密理博,05-449,Anti-Bin1 Antibody, clone 99D
merck millipore,默克密理博,371751,Anti-Gqα- and G₁₁α-Subunits, C-Terminal Rabbit pAb
merck millipore,默克密理博,MDCPN2M50,96 孔 MultiScreen 深孔接收板，聚丙烯
merck millipore,默克密理博,14-550M,MAP Kinase 2/Erk2 Protein, active, Human, 250 µg
merck millipore,默克密理博,MAB2095,Anti-Sialyl Lewis A Antibody, clone KM231
merck millipore,默克密理博,MABT144,Anti-Alpha-Actinin 4 Antibody, clone EPR2533(2), rabbit monoclonal