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Replacement Information 描述 产品目录编号 14-512 品牌系列 Upstate
商名 - Upstate
描述 Axl Protein, active, 10 µg 概述 N-terminal His6-tagged, recombinant amino acids 473-end human Axl 参考 产品信息 应用 应用 Active, N-terminal His6-tagged, recombinant amino acids 473-end human Axl, for use in Kinase Assays. 主要应用 - Kinase Assay
生物信息 来源 expressed in Sf21 cells 品种 Human 特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. Entrez基因编号 - NM_021913.2
- NM_001699.3
Entrez基因汇总 The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified. 基因符号 - UFO
- AXL
蛋白靶 Axl 纯化方法 Ni2+/NTA-agarose 靶子系列 TK UniProt编号 - P30530
UniProt汇总 FUNCTION: SwissProt: P30530 # May function as a signal transducer between specific cell types of mesodermal origin.
SIZE: 887 amino acids; 97437 Da
SUBUNIT: Heterodimer and heterotetramer with GAS6.
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
DISEASE:SwissProt: P30530 # Has transforming potential in patients with chronic myeloproliferative disorder or chronic myelocytic leukemia.
SIMILARITY: SwissProt: P30530 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily. & Contains 2 fibronectin type-III domains. & Contains 2 Ig-like C2-type (immunoglobulin-like) domains. & Contains 1 protein kinase domain.理化信息 尺寸 材料信息 毒性学信息 GHS安全信息 安全信息 产品使用声明 质量保证 routinely evaluated by phosphorylation of Axl-tide 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 6 months at -70°C 包装信息 数量 10 µg 包装 Also available in 250 µg size --call for pricing and availability and reference catalog number 14-512M when ordering the 250 µg size. 运输信息 补充信息 规格
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