merck millipore,默克密理愽
  • merck millipore,默克密理博,654257,TNF-α Antagonist III, R-7050 - CAS 303997-35-5 - Calbiochem

  • merck millipore,默克密理博,654257,TNF-α Antagonist III, R-7050 - CAS 303997-35-5 - Calbiochem

    产品名称：TNF-α Antagonist III, R-7050 - CAS 303997-35-5 - Calbiochem
    产品型号：654257
    The TNF-α Antagonist III, R-7050, also referenced under CAS 303997-35-5, controls the biological activity of TNF-α.

    merck millipore,默克密理博,654257,TNF-α Antagonist III, R-7050 - CAS 303997-35-5 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,654257,TNF-α Antagonist III, R-7050 - CAS 303997-35-5 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₆H₈ClF₃N₄S303997-35-5
    描述
    概述 A cell-permeable triazoloquinoxaline compound that acts as a TNF-α receptor antagonist via the blockage of receptor-adaptor molecules complex formation and subsequent receptor internalization, but not TNF-α ligand-receptor binding. Shown to selectively inhibit TNF-α-, but not Fas- or C6-ceramide-, induced caspase activation and cell death in ME180 cells and exhibit higher potency against TNF-α-induced than IL-1β-induced NF-κB activation (EC50 = 0.631 and 1.45 µM, respectively) in A549 cells.
    产品目录编号 654257
    品牌系列 Calbiochem®
    同义词 8-Chloro-4-(phenylsulfanyl)-1-(trifluoromethyl)[1,2,4]triazolo[4,3-a]quinoxaline
    参考
    参考 Gururaja, T.L., et al. 2007. Chem. Biol. 14, 1105.
    产品信息
    CAS号 303997-35-5
    形式 Light yellow powder
    Hill配方 C₁₆H₈ClF₃N₄S
    化学配方 C₁₆H₈ClF₃N₄S
    Molar Mass 380.8
    结构配方图像
    生物信息
    纯度 ≥97% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,654257,TNF-α Antagonist III, R-7050 - CAS 303997-35-5 - Calbiochem

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下一件merck millipore产品：merck millipore,默克密理博,AB9678,Anti-GABA A Receptor α 5 Antibody


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