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merck millipore,默克密理博,14-458M,CSK Protein, active, 250 µg
产品名称:CSK Protein, active, 250 µg
产品型号:14-458M
Active, recombinant full-length human CSK, containing an N-terminal GST-tag incorporating a PreScission Protease cleavage site, for use in Kinase Assays.
merck millipore,默克密理博,14-458M,CSK Protein, active, 250 µg
- 产品介绍
描述 产品目录编号 14-458M 品牌系列 Upstate
商名 - Upstate
描述 CSK Protein, active, 250 µg 概述 Recombinant full-length human CSK, containing an N-terminal GST-tag incorporating a PreScission Protease cleavage site 应用 应用 Active, recombinant full-length human CSK, containing an N-terminal GST-tag incorporating a PreScission Protease cleavage site, for use in Kinase Assays. 主要应用 - Kinase Assay
生物信息 来源 Expressed in E. coli BL21 (DE3) cells 品种 Human 特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. Entrez基因编号 - NM_004383.1
基因符号 - MGC117393
- CSK
蛋白靶 CSK 纯化方法 GSH-agarose chromatography 靶子系列 TK UniProt编号 - P41240
UniProt汇总 FUNCTION: SwissProt: P41240 # Specifically phosphorylates 'Tyr-504' on LCK, which acts as a negative regulatory site. Can also act on the LYN and FYN kinases.
SIZE: 450 amino acids; 50704 Da
SUBUNIT: Interacts with PTPN8 (By similarity). Interacts with phosphorylated SIT1, PAG1, LIME1 and TGFB1I1.
SUBCELLULAR LOCATION: Cytoplasm (By similarity). Cell membrane (By similarity). Note=Mainly cytoplasmic, also present in lipid rafts (By similarity).
TISSUE SPECIFICITY: Expressed in lung and macrophages.
PTM: Autophosphorylation of Tyr-304 occurs only at abnormally high CSK concentrations in vitro.
SIMILARITY: SwissProt: P41240 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily. & Contains 1 protein kinase domain. & Contains 1 SH2 domain. & Contains 1 SH3 domain.产品使用声明 质量保证 routinely evaluated by phosphorylation of Poly (Glu4Tyr) substrate peptide 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 1 year at -20°C 包装信息 数量 250 µg 包装 Also available in 10 μg size (cat#14-458) and in bulk (cat# 14-458-K).
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