merck millipore,默克密理愽
  • merck millipore,默克密理博,123850,AKR1C1 Inhibitor, 5-PBSA - CAS 4906-68-7 - Calbiochem

  • merck millipore,默克密理博,123850,AKR1C1 Inhibitor, 5-PBSA - CAS 4906-68-7 - Calbiochem

    产品名称：AKR1C1 Inhibitor, 5-PBSA - CAS 4906-68-7 - Calbiochem
    产品型号：123850
    The AKR1C1 Inhibitor, 5-PBSA, also referenced under CAS 4906-68-7, controls the biological activity of AKR1C1.

    merck millipore,默克密理博,123850,AKR1C1 Inhibitor, 5-PBSA - CAS 4906-68-7 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,123850,AKR1C1 Inhibitor, 5-PBSA - CAS 4906-68-7 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₃H₉BrO₃4906-68-7
    描述
    概述 A cell-permeable salicylic acid compound that acts as a highly potent, active-site directed and substrate competitive AKR1C1 inhibitor (Ki = 4 nM) with moderate to excellent selectivity over AKR1C2, AKR1C3 and AKR1C4 (Ki = 0.087, 4.2 and 18.2 µM, respectively). Shown to inhibit the metabolism of progesterone by AKR1C1 (IC50 = 460 nM in AKR1C1 overexpressing BAECs).
    产品目录编号 123850
    品牌系列 Calbiochem®
    同义词 Aldo-Keto Reductase family 1 member C1 Inhibitor, 5-PBSA, 3-Bromo-5-phenylsalicylic acid, 20α-Hydroxysteroid Dehydrogenase Inhibitor, 5-PBSA
    参考
    参考 El-Kabbani, O., et al. 2011. J. Steroid Biochem. Mol. Biol. 125, 105.
    El-Kabbani, O., et al. 2009. J. Med. Chem. 52, 3259.
    产品信息
    CAS号 4906-68-7
    形式 White solid
    Hill配方 C₁₃H₉BrO₃
    化学配方 C₁₃H₉BrO₃
    Molar Mass 293.1
    结构配方图像
    生物信息
    纯度 ≥94% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,123850,AKR1C1 Inhibitor, 5-PBSA - CAS 4906-68-7 - Calbiochem

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