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描述 概述 Native α1-acid glycoprotein from human plasma. Glycoprotein used for the study of the structure of oligosaccharide units. Consists of 40 - 45% carbohydrate. Present in human plasma at concentrations of 55 - 140 mg/100 ml. Clinically, α1-AG is an acute-phase reactant that, together with haptoglobin, indicates acute inflammation. Selectively suppresses the augmentation of NK cell activity by IFN-α and IFN-γ. The α1-AG:α1-antitrypsin ratio is useful in diagnosis of liver disease. A sialic acid-deficient α1-AG has been observed in serum or urine of patients with Hodgkin’s disease, psoriatic arthritis, diabetes, and chronic myeloid leukemia. Sialic acid-deficient α1-AG has an affinity for vitamin B12. 产品目录编号 112251 品牌系列 Calbiochem®
同义词 α₁-AG, C-AGP, Orosomucoid, α₁M-Seromucoid 参考 参考 Aso, H., et al. 1999. Inflammation 23, 117.
Schmid, K., et al. 1973. Biochemistry 12, 2711.产品信息 CAS号 66455-27-4 形式 Lyophilized Molar Mass 44100 生物信息 纯度 ≥95% by SDS-PAGE 来源 Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV. 理化信息 溶解度 aqueous buffers 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 +2°C to +8°C
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for to 3 months at (-20°C).
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