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merck millipore,默克密理博,09-718,Anti-TGIF2 Antibody
产品名称:Anti-TGIF2 Antibody
产品型号:09-718
Anti-TGIF2 Antibody is a Rabbit Polyclonal Antibody for detection of TGIF2 also known as transcription growth factor-beta-induced factor 2 & has been validated in WB.
merck millipore,默克密理博,09-718,Anti-TGIF2 Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H, M WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 09-718 品牌系列 Upstate
商名 - Upstate
描述 Anti-TGIF2 Antibody Alternate Names - transcription growth factor-beta-induced factor 2
- TGFB-induced factor homeobox 2
背景信息 TGIF2 (TGFbeta-induced transcription factor 2) is a homeobox protein that represses transcription by directly binding the DNA sequence 5'-CTGTCAA-3' or by interacting with the transcriptional modulator SMAD3. TGIF2 also is thought to repress transcription via the recruitment of histone deacetylase proteins. TGIF2 is phosphorylated in response to EGF signaling by the Ras/MAPK pathway. TGIF2 is amplified and overexpressed in several ovarian cancer cell lines. 产品信息 格式 Affinity Purified 演示 Immunoaffinity purified rabbit IgG in PBS, 0.1% sodium azide, 30% glycerol 应用 应用 Anti-TGIF2 Antibody is a Rabbit Polyclonal Antibody for detection of TGIF2 also known as transcription growth factor-beta-induced factor 2 & has been validated in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 KLH conjugated synthetic peptide (C)-EQDKEDFSSFQLLVE corresponding to a.a. 189-203 of human TGIF. 表位 a.a. 189-203 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Recognizes TGIF2 品种反应性 RatHumanMouse 抗体类型 Polyclonal Antibody Entrez基因编号 - 60436
Entrez基因汇总 The protein encoded by this gene is a DNA-binding homeobox protein and a transcriptional repressor.
The encoded protein appears to repress transcription by recruiting histone deacetylases to TGFbeta-responsive genes. This gene is amplified and overexpressed in some ovarian cancers, and mutations in this gene can cause holoprosencephaly.纯化方法 Immunoaffinity purified UniProt编号 - Q9GZN2
UniProt汇总 Transcription factor that controls the expression of the TH1 cytokine, interferon-gamma. Initiates TH1 lineage development from naive TH precursor cells both by activating TH1 genetic programs and by repressing the opposing TH2 programs. 产品使用声明 质量保证 Routinely evaluated by immunoblot. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
包装信息 数量 100 µg
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