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merck millipore,默克密理博,HTS061RTA,Ready-to-Assay™ CysLT1 Leukotriene Receptor Frozen Cells
产品名称：Ready-to-Assay™ CysLT1 Leukotriene Receptor Frozen Cells
产品型号：HTS061RTA
Human CysLT1 GPCR frozen cells for Calcium Flux FLIPR Assays.
merck millipore,默克密理博,HTS061RTA,Ready-to-Assay™ CysLT1 Leukotriene Receptor Frozen Cells
- 产品介绍
重要规格表
应用说明 品种 宿主细胞 蛋白靶 Calcium Flux Assays Human Chem-1 CysLT1 描述 产品目录编号 HTS061RTA 商名 - Ready-to-Assay
描述 Ready-to-Assay™ CysLT1 Leukotriene Receptor Frozen Cells 概述 TRANSFECTION: Full-length human CYSLTR1 cDNA 背景信息 Millipore’s Ready-to-Assay GPCR frozen cells are designed for simple, rapid calcium assays with no requirement for intensive cell culturing. Millipore has optimized the freezing conditions to provide cells with high viability and functionality post-thaw. The user simply thaws the cells and resuspends them in media, dispenses cell suspension into assay plates and, following over night recovery, assays for calcium response.
The cysteinyl leukotrienes, leukotriene C4, leukotriene D4 and leukotriene E4, are arachidonic acid derivatives modified by glutathione, Cys-Gly or Cys. Activated mast cells release cysteinyl leukotrienes, which cause smooth muscle contraction, airway constriction, and vascular permeability. The biological effects of the cysteinyl leukotrienes are mediated by two GPCRs, CysLT1 and CysLT2. A CysLT1 selective antagonist, montelukast, is used clinically in the treatment of asthma (Brink et al., 2003; Evans, 2002). Chemicon's cloned human CysLT1-expressing cell line is made in the Chem-1 host, which supports high levels of recombinant CysLT1 expression on the cell surface and contains high levels of the promiscuous G protein Galpha15 to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for antagonists of interactions between CysLT1 and its ligands.产品信息 部件 - Fifty (50) mL of Media Component.
- Pack contains 2 vials of mycoplasma-free cells, 1 ml per vial.
应用 应用 Human CysLT1 GPCR frozen cells for Calcium Flux FLIPR Assays. 应用说明 Calcium Flux Assays 生物信息 品种 Human GPCR类别 A 宿主细胞 Chem-1 蛋白靶 CysLT1 靶子系列 Leukotriene 细胞系类型 - Ready-to-Assay
产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
- This product contains genetically modified organisms (GMO). Within the EU GMOs are regulated by Directives 2001/18/EC and 2009/41/EC of the European Parliament and of the Council and their national implementation in the member States respectively. This legislation obliges Merck-Millipore to request certain information about you and the establishment where the GMOs are being handled.
储存和货运信息 存储条件 Place cells in liquid nitrogen immediately upon receipt. 包装信息 数量 1 kit
上一件merck millipore产品：merck millipore,默克密理博,324626,EGTA, Molecular Biology Grade - CAS 67-42-5 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,AB10410,Anti-YES (Proto-oncogene c-Yes) Antibody
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