merck millipore,默克密理愽
  • merck millipore,默克密理博,09-278,Anti-20S proteasome subunit β5 Antibody

  • merck millipore,默克密理博,09-278,Anti-20S proteasome subunit β5 Antibody

    产品名称：Anti-20S proteasome subunit β5 Antibody
    产品型号：09-278
    This Anti-20S proteasome subunit β5 Antibody is validated for use in IH, WB for the detection of 20S proteasome subunit β5.

    merck millipore,默克密理博,09-278,Anti-20S proteasome subunit β5 Antibody

  • 产品介绍
  • merck millipore,默克密理博,09-278,Anti-20S proteasome subunit β5 Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HWB, IHCRbSerumPolyclonal Antibody
    描述
    产品目录编号 09-278
    品牌系列 Upstate
    商名
    • Upstate
    描述 Anti-20S proteasome subunit β5 Antibody
    Alternate Names
    • MB1
    • LMP17
    产品信息
    格式 Serum
    演示 100 µL of purified antiserum preparation in PBS containing 0.01M sodium azide. Dilute to working strength with phosphate buffered saline pH 7.2-7.4.
    应用
    应用 This Anti-20S proteasome subunit β5 Antibody is validated for use in IH, WB for the detection of 20S proteasome subunit β5.
    主要应用
    • Western Blotting
    • Immunohistochemistry
    生物信息
    免疫原品种 Peptide corresponding to residues 194-207 of human proteasome subunit β5 conjugated to KLH.
    宿主 Rabbit
    特异性 Recognizes proteasome subunit β5
    同种型 IgG
    品种反应性 Human
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_002797.2
    Entrez基因汇总 The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit).
    基因符号
    • MB1
    • PSMB5
    • X
    • LMPX
    • MGC104214
    纯化方法 Serum
    UniProt编号
    • P28074
    UniProt汇总 FUNCTION: SwissProt: P28074 # The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. May catalyze basal processing of intracellular antigens.
    SIZE: 208 amino acids; 22897 Da
    SUBUNIT: The proteasome is composed of at least 15 non identical subunits which form a highly ordered ring-shaped structure. This subunit can be displaced by the equivalent immune-specific subunit PSMB8. Directly interacts with POMP.
    SUBCELLULAR LOCATION: Cytoplasm. Nucleus.
    SIMILARITY: SwissProt: P28074 ## Belongs to the peptidase T1B family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at -20°C from date of shipment for up to 12 months.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,09-278,Anti-20S proteasome subunit β5 Antibody

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