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品种反应性 主要应用 宿主 格式 抗体类型 R, H, M WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 07-794 品牌系列 Upstate
商名 - Upstate
描述 Anti-Rab13 Antibody 背景信息 Rab proteins are members of the Ras superfamily of small G-Proteins. At least 60 isoforms have been identified. These GTPases are primarily involved in vesicle trafficking and it is believed that a different Rab protein may be needed for each step of the vesicular transport. It is thought Rab4 and Rab11 are involved in internalization, sorting, and transport to lysosomes or recycling, of several membrane proteins, including GPCRs, GLUT-4, Aquaporin-2, or the H+/K+ ATPase. 产品信息 格式 Affinity Purified 控制 - PC12 Cell Lysate
演示 Affinity Purified rabbit IgG in storage buffer containing tri-citrate-phosphate, pH 7-8 and 0.1% sodium azide. 应用 应用 Detect Rab13 using this Anti-Rab13 Antibody validated for use in WB, IP & IF. 主要应用 - Western Blotting
应用说明 Immunofluorescence Staining:
Independent laboratory demonstrated this antibody worked in Immunofluorescence studies at a 1:100-1:500 dilution.
Immunoprecipitation (IP):
Independent laboratory demonstrated this antibody works in Immunoprecipitation.
生物信息 免疫原品种 Sythnetic peptide of amno acids 129-148 of rat Rab13 宿主 Rabbit 特异性 Recognizes Rab13 品种反应性 RatHumanMouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_002861
基因符号 - growth-inhibiting gene 4 protein
- Rab13
- RAB13, member RAS oncogene family
- GIG4
UniProt编号 - P51153
UniProt汇总 FUNCTION: Could participate in polarized transport, in the assembly and/or the activity of tight junctions.
SIZE: 203 amino acids; 22,774 Da
SUBCELLULAR LOCATION:Cell junction › tight junction. Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle membrane; Lipid-anchor; Cytoplasmic side. Note= Cytoplasmic tight junctions or associated with vesicles scattered throughout the cytoplasm in cells lacking tight junctions.
TISSUE SPECIFICITY: Detected in several types of epithelia, including intestine, kidney, liver and in endothelial cells.
SIMILARITY: Belongs to the small GTPase superfamily. Rab family.产品使用声明 质量保证 Western Blot Analysis:
This lot detected Rab13 at 1:1,000 (1g/mL) dilution in lysates from PC12 lysate resolved via SDS-PAGE and transferred to PVDF (Immobilon-P).使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt.
Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
包装信息 数量 100 µg
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