merck millipore,默克密理愽
  • merck millipore,默克密理博,04-639,Anti-PP2A Antibody, B subunit, B56 delta, clone H5D12

  • merck millipore,默克密理博,04-639,Anti-PP2A Antibody, B subunit, B56 delta, clone H5D12

    产品名称：Anti-PP2A Antibody, B subunit, B56 delta, clone H5D12
    产品型号：04-639
    This Anti-PP2A Antibody, B subunit, B56 delta, clone H5D12 is validated for use in WB for the detection of PP2A.

    merck millipore,默克密理博,04-639,Anti-PP2A Antibody, B subunit, B56 delta, clone H5D12

  • 产品介绍
  • merck millipore,默克密理博,04-639,Anti-PP2A Antibody, B subunit, B56 delta, clone H5D12

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HWBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 04-639
    品牌系列 Upstate
    商名
    • Upstate
    描述 Anti-PP2A Antibody, B subunit, B56 delta, clone H5D12
    背景信息 PP2A is a heterotrimeric phosphatase, ccomposed of A, B and C subunits. The structural A and catalytic C subunits form the constitutive core of the enzyme, which associates with one of a large number of regulatory B subunits. Three families of B subunits have been identified thus far. The prototypical B (or PR55) family of subunits is encoded by three genes, Balpha, Bbeta and Bgamma . The B' (or B56) family consists of at least seven splice variantsderived from five genes. RNA's for the two members of the B'' family, PR72 and PR130, arise by alternative splicing or use of alternate transcription start sites from the same gene. Primary structures as well as functions of B and B' subunits are conserved from yeast to mammals.
    产品信息
    格式 Purified
    演示 Purified mouse monoclonal IgG1 antibody in PBS with 0.05% NaN3.
    应用
    应用 This Anti-PP2A Antibody, B subunit, B56 delta, clone H5D12 is validated for use in WB for the detection of PP2A.
    主要应用
    • Western Blotting
    应用说明 Immunoblotting (1:500 to 1:2000)

    Optimal working dilutions must be determined by the end user
    生物信息
    免疫原品种 GST fusion protein corresponding to the N-terminus of human PP2A, B subunit, B56 delta
    克隆 H5D12
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 Human PP2A, B subunit, B56 delta. This monoclonal antibody is the delta isoform for the B56 family of protein phosphatase 2A.
    同种型 IgG1
    品种反应性 Human
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_006245
    Entrez基因汇总 The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an delta isoform of the regulatory subunit B56 subfamily.
    基因符号
    • MGC8949
    • PPP2R5D
    • B56D
    • MGC2134
    UniProt编号
    • Q14738
    UniProt汇总 FUNCTION: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
    SUBUNIT: PP2A consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules.
    TISSUE SPECIFICITY: Isoform Delta-2 is widely expressed. Isoform Delta-1 is highly expressed in brain.
    INDUCTION: By retinoic acid; in neuroblastoma cell lines.
    PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.
    SIMILARITY: Belongs to the phosphatase 2A regulatory subunit B56 family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,04-639,Anti-PP2A Antibody, B subunit, B56 delta, clone H5D12

上一件merck millipore产品：merck millipore,默克密理博,SF002-100,ESGRO Complete Basal Medium, 100mL
下一件merck millipore产品：merck millipore,默克密理博,627610,Caspase Inhibitor I - CAS 187389-52-2 - Calbiochem


相关产品

merck millipore,默克密理博,219393,Cathepsin S Inhibitor - Calbiochem merck millipore,默克密理博,219393,Cathepsin S Inhibitor - Calbiochem

merck millipore,默克密理博,07-794,Anti-Rab13 Antibody merck millipore,默克密理博,07-794,Anti-Rab13 Antibody

merck millipore,默克密理博,MAB8582,Anti-RSV Antibody, fusion protein, all type B strains, clone 102-10B merck millipore,默克密理博,MAB8582,Anti-RSV Antibody, fusion protein, all type B strains, clone 102-10B

merck millipore,默克密理博,524572,Phosphatase, Alkaline, Calf Intestine merck millipore,默克密理博,524572,Phosphatase, Alkaline, Calf Intestine

merck millipore,默克密理博,SF002-100,ESGRO Complete Basal Medium, 100mL merck millipore,默克密理博,SF002-100,ESGRO Complete Basal Medium, 100mL

merck millipore,默克密理博,627610,Caspase Inhibitor I - CAS 187389-52-2 - Calbiochem merck millipore,默克密理博,627610,Caspase Inhibitor I - CAS 187389-52-2 - Calbiochem

merck millipore,默克密理博,DR1098,Anti-ID1 Mouse mAb (1F7) merck millipore,默克密理博,DR1098,Anti-ID1 Mouse mAb (1F7)

merck millipore,默克密理博,521000,Phenylarsine Oxide - CAS 637-03-6 - Calbiochem merck millipore,默克密理博,521000,Phenylarsine Oxide - CAS 637-03-6 - Calbiochem

merck millipore,默克密理博,AP503R,Goat Anti-Mouse IgG γ chain Antibody, TRITC conjugate, Species Adsorbed merck millipore,默克密理博,AP503R,Goat Anti-Mouse IgG γ chain Antibody, TRITC conjugate, Species Adsorbed

merck millipore,默克密理博,344930,Furin Inhibitor I - Calbiochem merck millipore,默克密理博,344930,Furin Inhibitor I - Calbiochem


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部