- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
-
-
merck millipore,默克密理博,ABN73,Anti-Neutral amino acid transporter (ASCT2) Antibody
产品名称：Anti-Neutral amino acid transporter (ASCT2) Antibody
产品型号：ABN73
Anti-Neutral amino acid transporter (ASCT2) Antibody detects level of Neutral amino acid transporter (ASCT2) & has been published & validated for use in WB, IH(P).
merck millipore,默克密理博,ABN73,Anti-Neutral amino acid transporter (ASCT2) Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABN73 描述 Anti-Neutral amino acid transporter (ASCT2) Antibody Alternate Names - Solute carrier family 1 member 5
- Neutral amino acid transporter B(0)
- Baboon M7 virus receptor
- RD114/simian type D retrovirus receptor
- Sodium-dependent neutral amino acid transporter type 2
背景信息 Neutral amino acid transporter, also known as ASCT2, is an alternate of the ASC (alanine-, serine-, cysteine-) transport system and is highly expressed in rat astroglia-rich cultures while not highly expressed in rat neuron-rich cultures. ASCT2 is also thought to be important in the glutamine release from cells. ASCT2 has been implicated in the growth and survival of cancer cells, therefore making it a possible target for cancer therapy. ASCT2 is thought to be a crucial neuronal neutral amino acid transporter. 产品信息 格式 Affinity Purified 控制 - Human placenta tissue lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-Neutral amino acid transporter (ASCT2) Antibody detects level of Neutral amino acid transporter (ASCT2) & has been published & validated for use in WB, IH(P). 主要应用 - Western Blotting
应用说明 Immunohistochemistry Analysis: 1:1000 dilution from a previous lot detected Neutral amino acid transporter in human prostate tissue. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to the N-terminus of Neutral amino acid transporter. 表位 N-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes Neutral amino acid transporter at the N-terminus. 品种反应性 Human Species Reactivity Note Demonstrated to react with human. No homology found to mouse or rat.
Other homologies: rhesus monkey (93% sequence homology).抗体类型 Polyclonal Antibody Entrez基因编号 - NP_005619
Entrez基因汇总 The SLC1A5 gene encodes a sodium-dependent neutral amino acid transporter that can act as a receptor for RD114/type D retrovirus (Larriba et al., 2001 [PubMed 11781704]).[supplied by OMIM]. 基因符号 - RDRC
- SLC1A5
- M7V1
- AAAT
- R16
- ATBO
- M7VS1
- RDR
- ATB
- ASCT2
纯化方法 Affinity purified UniProt编号 - Q15758
UniProt汇总 FUNCTION: Has a broad substrate specificity, a preference for zwitterionic amino acids, and a sodium-dependence. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated amino acids, anionic amino acids, and cationic amino acids. Act as a cell surface receptor for feline endogenous virus RD114, baboon M7 endogenous virus and type D simian retroviruses. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Probable). Melanosome. Note: Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
TISSUE SPECIFICITY: Placenta, lung, skeletal muscle, kidney, pancreas, and intestine.
SEQUENCE SIMILARITIES: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A5 subfamily.产品使用声明 质量保证 Evaluated by Western Blot in human placenta tissue lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected Neutral amino acid transporter on 10 µg of human placenta tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,AB17003,Anti-Bim Antibody, internal epitope, pan-Bim isoforms
下一件merck millipore产品：merck millipore,默克密理博,219393,Cathepsin S Inhibitor - Calbiochem
相关产品
merck millipore,默克密理博,AB15014,Anti-Glycine Receptor α3 subunit Antibody
merck millipore,默克密理博,AB5460-50UL,Anti-Acid Sensitive Ion Channel 2 Antibody, neuronal
merck millipore,默克密理博,SF-1273,UCHL1; Human, Cyanine 5 RNA Detection Probe,SmartFlare
merck millipore,默克密理博,AB17003,Anti-Bim Antibody, internal epitope, pan-Bim isoforms
merck millipore,默克密理博,219393,Cathepsin S Inhibitor - Calbiochem
merck millipore,默克密理博,07-794,Anti-Rab13 Antibody
merck millipore,默克密理博,MAB8582,Anti-RSV Antibody, fusion protein, all type B strains, clone 102-10B
merck millipore,默克密理博,524572,Phosphatase, Alkaline, Calf Intestine
merck millipore,默克密理博,SF002-100,ESGRO Complete Basal Medium, 100mL