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品种反应性 主要应用 宿主 格式 抗体类型 Yeast (S. cerevisiae), B, Dr, H, R WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 07-760 Replaces 04-342 品牌系列 Upstate
商名 - Upstate
描述 Anti-phospho-eIF-2α (Ser51) Antibody 产品信息 格式 Affinity Purified 应用 应用 Anti-phospho-eIF-2α (Ser51) Antibody is an antibody against phospho-eIF-2α (Ser51) for use in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 KLH-conjugated, synthetic peptide (SEL[pS]RRRIRSINK) corresponding to amino acids 48-60 of Drosophila eIF-2α. 宿主 Rabbit 特异性 phospho-eIF-2α; Ser51 in Drosophila corresponds to Ser52 in human, rat, bovine and yeast eIF-2α 同种型 IgG 品种反应性 Yeast (S. cerevisiae)BovineDrosophilaHumanRat 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_032025.3
Entrez基因汇总 EIF2A is a 65-kD protein that catalyzes the formation of puromycin-sensitive 80S preinitiation complexes (Zoll et al., 2002 [PubMed 12133843]).[supplied by OMIM] 基因符号 - MST089
- EIF2A
- MSTP089
- eIF-2A
- MSTP004
- ORFNames=CDA02
- EIF-2A
- CDA02
修改 - Phosphorylation
纯化方法 Immunoaffinity purified UniProt编号 - Q9BY44
UniProt汇总 FUNCTION: SwissProt: Q9BY44 # Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF- 2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon- dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins.
SIZE: 585 amino acids; 64976 Da
TISSUE SPECIFICITY: Widely expressed. Expressed at higher level in pancreas, heart, brain and placenta.
SIMILARITY: SwissProt: Q9BY44 ## Belongs to the WD repeat EIF2A family. & Contains 3 WD repeats.产品使用声明 质量保证 Routinely evaluated by immunoblot on recombinant eIF-2α phosphorylated by recombinant PKR (Cat. # 14-423) 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 1 year at -20°C from date of shipment 包装信息 数量 100 µL
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