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品种反应性 主要应用 宿主 格式 抗体类型 R WB Rb Purified Polyclonal Antibody 描述 产品目录编号 07-704 品牌系列 Upstate
商名 - Upstate
描述 Anti-EC-SOD Antibody 产品信息 格式 Purified 应用 应用 Detect EC-SOD using this Anti-EC-SOD Antibody validated for use in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 KLH-conjugated, synthetic peptide corresponding to the sequence 227-236 (ERKKRRRESE-C) which corresponds to human EC-SOD (extracellular superoxide dismutase or SOD3) with a c-terminal cysteine added for conjugation purposes. The immunizing sequence is identical in mouse, rat, chimpanzee, chicken, cow, dog, rabbit, and yeast. 宿主 Rabbit 特异性 Rat. Broad species cross-reactivity is expected. 同种型 IgG 品种反应性 Rat Species Reactivity Note Broad species cross-reactivity is expected. 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_003102.2
Entrez基因汇总 This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. The product of this gene is thought to protect the brain, lungs, and other tissues from oxidative stress. The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix (ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the ECM. 基因符号 - EC-SOD
- SOD3
- MGC20077
- Cu-Znprecursor
纯化方法 Protein A purfied UniProt编号 - P08294
UniProt汇总 FUNCTION: SwissProt: P08294 # Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
COFACTOR: Binds 1 copper ion per subunit (By similarity). & Binds 1 zinc ion per subunit (By similarity).
SIZE: 240 amino acids; 25851 Da
SUBUNIT: Homotetramer.
SUBCELLULAR LOCATION: Secreted, extracellular space. Note=99% of EC-SOD is anchored to heparan sulfate proteoglycans in the tissue interstitium, and 1% is located in the vasculature in equilibrium between the plasma and the endothelium.
TISSUE SPECIFICITY: Major SOD isoenzyme in extracellular fluids such as plasma, lymph and synovial fluid.
SIMILARITY: SwissProt: P08294 ## Belongs to the Cu-Zn superoxide dismutase family.产品使用声明 质量保证 Routinely evaluated by immunoblot. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C from date of shipment 包装信息 数量 200 µg
上一件merck millipore产品：merck millipore,默克密理博,GF424,HumanKine IL-23, Human Recombinant Xeno-Free
下一件merck millipore产品：merck millipore,默克密理博,220588,Chlorophenolred-β-D-galactopyranoside, Sodium Salt
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