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品种反应性 主要应用 宿主 格式 抗体类型 R, H, M WB, IHC Rb Purified Polyclonal Antibody 描述 产品目录编号 07-633 品牌系列 Upstate
商名 - Upstate
描述 Anti-HNF3β/FOXA2 Antibody 背景信息 This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporatic cases of maturity-onset diabetes of the young. Two transcript variants encoding the same protein have been identified for this gene. 产品信息 格式 Purified 控制 - MLE 12 nuclear extracts, human liver lysate
演示 Protein A Purified rabbit IgG in a solution of 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.135M NaCl, and 0.035% sodium azide as a preservative. 应用 应用 Detect HNF3β/FOXA2 with Anti-HNF3β/FOXA2 Antibody (Rabbit Polyclonal Antibody), that has been shown to work in IHC & WB. 主要应用 - Western Blotting
- Immunohistochemistry
生物信息 免疫原品种 GST fusion protein corresponding to residues 7-86 of rat hepatocyte nuclear factor-3 beta / forkhead box A2 (HNF3β/FOXA2) 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Recognizes HNF3β/FOXA2. 同种型 IgG 品种反应性 RatHumanMouse 抗体类型 Polyclonal Antibody Entrez基因汇总 This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Two transcript variants encoding the same protein have been identified for this gene. 基因符号 - HNF3B
- FOXA2
- MGC19807
- HNF-3B
- TCF3B
纯化方法 Protein A purfied UniProt编号 - Q9Y261
UniProt汇总 FUNCTION: SwissProt: Q9Y261 # Transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes.
SIZE: 457 amino acids; 48306 Da
SUBUNIT: Binds TLE1 (By similarity).
SUBCELLULAR LOCATION: Nucleus.
SIMILARITY: SwissProt: Q9Y261 ## Contains 1 fork-head DNA-binding domain.产品使用声明 质量保证 Routinely evaluated by immunoblot with nuclear extracts from MLE 12 cells 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 包装信息 数量 200 µg
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