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merck millipore,默克密理博,513024,PD 151746 - CAS 179461-52-0 - Calbiochem
产品名称:PD 151746 - CAS 179461-52-0 - Calbiochem
产品型号:513024
A cell-permeable, non-peptidic, and highly selective calpain inhibitor directed towards the calcium binding sites of calpain.
merck millipore,默克密理博,513024,PD 151746 - CAS 179461-52-0 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₁₁H₈FNO₂ 179461-52-0 描述 概述 A cell-permeable, non-peptidic, and highly selective calpain inhibitor directed towards the calcium binding sites of calpain. Displays over 20-fold greater selectivity for calpain-1 (Cat. Nos. 208712 and 208713) over calpain-2 (Cat. Nos. 208715 and 208718) (Ki values: 260 nM and 5.33 µM, respectively). Has been shown to prevent cycloheximide-induced apoptosis. 产品目录编号 513024 品牌系列 Calbiochem®
同义词 3-(5-Fluoro-3-indolyl)-2-mercapto-(Z)-2-propenoic Acid 参考 参考 Squier, M.K., et al. 1999. J. Cell Physiol. 178, 311.
Wang, K.K., et al. 1996. Proc. Natl. Acad. Sci. USA 93, 6687.产品信息 CAS号 179461-52-0 具有ATP竞争性 N 形式 Orange solid Hill配方 C₁₁H₈FNO₂ 化学配方 C₁₁H₈FNO₂ Molar Mass 237.3 可逆 N 结构配方图像 生物信息 主靶 calpain-1 主靶Ki 260 nM against calpain-1 纯度 ≥95% by HPLC 理化信息 细胞可渗透 Y 溶解度 DMSO or MeOH 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
避光 Protect from light
无需冷冻 No
特殊指南 Unstable in solution; reconstitute just prior to use. 包装信息 惰性气体下包装 Packaged under inert gas
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