merck millipore,默克密理愽
  • merck millipore,默克密理博,420143,JNK3 Inhibitor XII, SR-3576 - CAS 1164153-22-3 - Calbiochem

  • merck millipore,默克密理博,420143,JNK3 Inhibitor XII, SR-3576 - CAS 1164153-22-3 - Calbiochem

    产品名称：JNK3 Inhibitor XII, SR-3576 - CAS 1164153-22-3 - Calbiochem
    产品型号：420143
    The JNK3 Inhibitor XII, SR-3576, also referenced under CAS 1164153-22-3, controls the biological activity of JNK3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylati More>>

    merck millipore,默克密理博,420143,JNK3 Inhibitor XII, SR-3576 - CAS 1164153-22-3 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,420143,JNK3 Inhibitor XII, SR-3576 - CAS 1164153-22-3 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₇H₂₇N₅O₅1164153-22-3
    描述
    概述 A cell-permeable pyrazolourea compound that acts as a potent, ATP binding pocket-targeting, and JNK3-selective inhibitor (IC50 = 7 nM), inhibiting JNK1 only at much higher concentrations (IC50 = 170 nM) and exhibiting little activity against p38 even at concentrations as high as 20 µM. Shown to inhibit streptozotocin- (Cat. No. 572201) induced c-jun phosphorylation in INS-1 rat β-pancreatic cells (IC50 = 1.3 µM).
    产品目录编号 420143
    品牌系列 Calbiochem®
    同义词 3-(4-(3-(3-Methylphenylureido))-1H-pyrazol-1-yl)-N-(3,4,5-trimethoxyphenyl)benzamide
    参考
    参考 Kamenecka, T., et al. 2009. J. Biol. Chem. 284, 12853.
    产品信息
    CAS号 1164153-22-3
    形式 Off-white solid
    Hill配方 C₂₇H₂₇N₅O₅
    化学配方 C₂₇H₂₇N₅O₅
    Molar Mass 501.5
    结构配方图像
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    溶解度 DMSO
    安全信息
    S相 S: 22-24/25

    Do not breathe dust.
    Avoid contact with skin and eyes.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,420143,JNK3 Inhibitor XII, SR-3576 - CAS 1164153-22-3 - Calbiochem

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