merck millipore,默克密理愽
  • merck millipore,默克密理博,06-1026,Anti-TM7SF2 Antibody

  • merck millipore,默克密理博,06-1026,Anti-TM7SF2 Antibody

    产品名称：Anti-TM7SF2 Antibody
    产品型号：06-1026
    Anti-TM7SF2 Antibody is a Rabbit Polyclonal Antibody for detection of TM7SF2 also known as Delta(14)-sterol reductase, Putative sterol reductase SR-1 & has been validated in WB, ICC.

    merck millipore,默克密理博,06-1026,Anti-TM7SF2 Antibody

  • 产品介绍
  • merck millipore,默克密理博,06-1026,Anti-TM7SF2 Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    Rhesus Macaque, H, BICC, WBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 06-1026
    描述 Anti-TM7SF2 Antibody
    Alternate Names
    • Transmembrane 7 superfamily member 2
    • Delta(14)-sterol reductase
    • Delta-14-SR
    • Another new gene 1 protein
    • C-14 sterol reductase
    • Putative sterol reductase SR-1
    • Sterol C14-reductase
    背景信息 Sterol Delta-14 reductase, also known as TM7SF2 and NET47, is important in the conversion of lanosterol to cholesterol, an essential cellular metabolic process, in many mammalian species. This protein is a multipass membrane protein typically found in the endoplasmic reticulum.
    产品信息
    格式 Affinity Purified
    控制
    • Human brain tissue lysate
    演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Anti-TM7SF2 Antibody is a Rabbit Polyclonal Antibody for detection of TM7SF2 also known as Delta(14)-sterol reductase, Putative sterol reductase SR-1 & has been validated in WB, ICC.
    主要应用
    • Immunocytochemistry
    • Western Blotting
    应用说明 Immunocytochemistry Analysis: A representative lot was used by an independent laboratory in HeLa cells. (Image courtesy of Dr. Eric C. Schirmer, The Wellcome Trust Centre for Cell Biology, University of Edinburgh)
    生物信息
    免疫原品种 KLH-conjugated linear peptide corresponding to human TM7SF2.
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    品种反应性 Rhesus MacaqueHumanBovine
    Species Reactivity Note Demonstrated to react with human. Predicted to react with bovine and rhesus monkey based on 100% sequence homology.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NP_003264.2
    基因符号
    • NET47
    • TM7SF2
    • ANG1
    纯化方法 Affinity purified
    UniProt编号
    • O76062
    UniProt汇总 FUNCTION: Involved in the conversion of lanosterol to cholesterol.

    CATALYTIC ACTIVITY: 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol + NADP+ = 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol + NADPH.

    SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Multi-pass membrane protein

    TISSUE SPECIFICTY: Expressed in adult heart, brain, pancreas, lung, liver, skeletal muscle, kidney, ovary, prostate, and testis, but not detected in placenta, spleen, thymus, small intestine, colon (mucosal lining), or peripheral blood leukocytes.

    SEQUENCE SIMILARITIES: Belongs to the ERG4/ERG24 family.

    SEQUENCE CAUTION: The sequence AAC21450.1 differs from that shown. Reason: Sequencing errors.

    The sequence AAC21457.1 differs from that shown. Reason: Sequencing errors.
    产品使用声明
    质量保证 Evaluated by Western Blot in human brain tissue lysate.

    Western Blot Analysis: 5 µg/mL of this antibody detected TM7SF2 on 10 µg of human brain tissue lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,06-1026,Anti-TM7SF2 Antibody

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