merck millipore,默克密理愽
  • merck millipore,默克密理博,361562,GSK-3β Inhibitor XVIII - CAS 1139875-74-3 - Calbiochem

  • merck millipore,默克密理博,361562,GSK-3β Inhibitor XVIII - CAS 1139875-74-3 - Calbiochem

    产品名称：GSK-3β Inhibitor XVIII - CAS 1139875-74-3 - Calbiochem
    产品型号：361562
    The GSK-3β Inhibitor XVIII, also referenced under CAS 1139875-74-3, controls the biological activity of GSK-3β. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation  More>>

    merck millipore,默克密理博,361562,GSK-3β Inhibitor XVIII - CAS 1139875-74-3 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,361562,GSK-3β Inhibitor XVIII - CAS 1139875-74-3 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₀H₂₀ClN₅OS1139875-74-3
    描述
    概述 A cell-permeable thienylpyrimidine compound that is reported to act as a potent and selective GSK-3β inhibitor (IC50 = 64 nM), while exhibiting little or no activity against 58 and much reduced potency against 7 (>75% inhibition at 5 µM) other kinases. Shown to activate cellular Wnt pathway signaling (EC50 = 1.25 µM in a Super (8X) TOPFlash reporter assay) in HEK293 cultures and promote proliferation of murine and hamster β cell lines (EC50 = 1.143 µM using murine R7T1 cultures) as well as of primary rat β cells.
    产品目录编号 361562
    品牌系列 Calbiochem®
    同义词 2-(Chloro-4-(4-thiophen-2-yl-pyrimidin-2-ylamino)-phenyl)-(4-methyl-pierazin-1-yl)-methanone
    参考
    参考 Wang, W., et al. 2009. Proc. Natl. Acad. Sci. USA 106, 1427.
    产品信息
    CAS号 1139875-74-3
    形式 White solid
    Hill配方 C₂₀H₂₀ClN₅OS
    化学配方 C₂₀H₂₀ClN₅OS
    Molar Mass 413.9
    结构配方图像
    生物信息
    纯度 ≥97% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,361562,GSK-3β Inhibitor XVIII - CAS 1139875-74-3 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,565834,sFRP-3, His•Tag, Mouse, Recombinant
下一件merck millipore产品：merck millipore,默克密理博,AB3570P,Anti-Organic Anion Transporting Polypeptide 1 Antibody


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