merck millipore,默克密理愽
  • merck millipore,默克密理博,07-398,Anti-phospho-NR2B (Ser1303) Antibody

  • merck millipore,默克密理博,07-398,Anti-phospho-NR2B (Ser1303) Antibody

    产品名称：Anti-phospho-NR2B (Ser1303) Antibody
    产品型号：07-398
    Anti-phospho-NR2B (Ser1303) Antibody detects level of phospho-NR2B (Ser1303) & has been published & validated for use in WB.

    merck millipore,默克密理博,07-398,Anti-phospho-NR2B (Ser1303) Antibody

  • 产品介绍
  • merck millipore,默克密理博,07-398,Anti-phospho-NR2B (Ser1303) Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, H, MWBRbPurifiedPolyclonal Antibody
    描述
    产品目录编号 07-398
    Replaces 04-1148
    品牌系列 Upstate
    商名
    • Upstate
    描述 Anti-phospho-NR2B (Ser1303) Antibody
    产品信息
    格式 Purified
    控制
    • Brain tissue
    演示 Protein A Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.
    应用
    应用 Anti-phospho-NR2B (Ser1303) Antibody detects level of phospho-NR2B (Ser1303) & has been published & validated for use in WB.
    主要应用
    • Western Blotting
    生物信息
    免疫原品种 Peptide corresponding to amino acids 1297-1309 of human phospho-NR2B
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Recognizes phospho-NR2B.
    同种型 IgG
    品种反应性 RatHumanMouse
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_000834
    Entrez基因汇总 N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.
    基因符号
    • NR3
    • GRIN2B
    • NR2B
    • MGC142180
    • Glutamate
    • NMDAR2B
    • MGC142178
    • hNR3
    修改
    • Phosphorylation
    纯化方法 Protein A purfied
    UniProt编号
    • Q13224
    UniProt汇总 FUNCTION: SwissProt: Q13224 # NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.
    SIZE: 1484 amino acids; 166367 Da
    SUBUNIT: Forms heteromeric channel of a zeta subunit (GRIN1), a epsilon subunit (GRIN2A, GRIN2B, GRIN2C or GRIN2D) and a third subunit (GRIN3A or GRIN3B). Found in a complex with GRIN1 and GRIN3B. Found in a complex with GRIN1, GRIN3A and PPP2CB. Interacts with PDZ domains of INADL and DLG4 (By similarity).
    SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
    TISSUE SPECIFICITY: Primarily found in the fronto-parieto-temporal cortex and hippocampus pyramidal cells, lower expression in the basal ganglia.
    SIMILARITY: SwissProt: Q13224 ## Belongs to the glutamate-gated ion channel (TC 1.A.10) family.
    产品使用声明
    质量保证 routinely evaluated by immunoblot in a rat brain microsomal protein preparation
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
    包装信息
    数量 200 µg

    merck millipore,默克密理博,07-398,Anti-phospho-NR2B (Ser1303) Antibody

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