- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Purified Polyclonal Antibody 描述 产品目录编号 07-167 品牌系列 Upstate
商名 - Upstate
描述 Anti-Blys/TALL-1/BAFF/THANK Antibody 产品信息 格式 Purified 演示 PBS containing 0.02% sodium azide 应用 应用 Anti-Blys/TALL-1/BAFF/THANK Antibody is an antibody against Blys/TALL-1/BAFF/THANK for use in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 peptide corresponding to amino acids 254-269 of human Blys (EEGDELQLAIPRENAQ) 宿主 Rabbit 特异性 Blys/TALL-1/BAFF/THANK 同种型 IgG 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_006573
Entrez基因汇总 The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. 基因符号 - BLYS
- TNFSF13B
- DTL
- TALL-1
- ZTNF4
- BLyS
- THANK
- TNFSF20
- CD257
- TALL1
- BAFF
纯化方法 Protein G chromatography UniProt编号 - Q9Y275
UniProt汇总 FUNCTION: SwissProt: Q9Y275 # Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response.
SIZE: 285 amino acids; 31223 Da
SUBUNIT: Homotrimer.
SUBCELLULAR LOCATION: Cell membrane; Single-pass type II membrane protein. & Tumor necrosis factor ligand superfamily member 13b, soluble form: Secreted.
TISSUE SPECIFICITY: Abundantly expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. Also found in the spleen, lymph node, bone marrow, T- cells and dendritic cells. A lower expression seen in placenta, heart, lung, fetal liver, thymus, and pancreas.
PTM: The soluble form derives from the membrane form by proteolytic processing. & N-glycosylated.
SIMILARITY: SwissProt: Q9Y275 ## Belongs to the tumor necrosis factor family.产品使用声明 质量保证 routinely evaluated by immunoblot on RIPA lysates from Jurkat cells or HeLa nuclear extract 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,438187,InSolution™ Lovastatin, Sodium Salt - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,CBS-KSP,Superchemiblock Heterophile Blocking Agent
相关产品
merck millipore,默克密理博,05-516,Anti-Ras Antibody, clone RAS10
merck millipore,默克密理博,04-970,Anti-Osteopontin Antibody, clone 6B6.2
merck millipore,默克密理博,AP184B,Donkey Anti-Sheep IgG Antibody, biotin-SP conjugate, Species Adsorbed
merck millipore,默克密理博,MAB8879,Anti-Cdk4 Antibody, clone DCS-35
merck millipore,默克密理博,438187,InSolution™ Lovastatin, Sodium Salt - Calbiochem
merck millipore,默克密理博,CBS-KSP,Superchemiblock Heterophile Blocking Agent
merck millipore,默克密理博,ABT69,Anti-CCDC53 Antibody
merck millipore,默克密理博,MABS64,Anti-phospho-p38 (Thr180/Tyr182) Antibody, clone 6E5.2
merck millipore,默克密理博,217538,β-Carotene - CAS 7235-40-7 - Calbiochem
