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Replacement Information Replacement Information 07-1404 is a recommended replacement for AB1346 重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M, H IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 07-1404 Replaces AB1346 描述 Anti-GLUT-4 Antibody, C-terminus Alternate Names - GLUT-4
- Solute carrier family 2, facilitated glucose transporter member 4
- Glucose transporter type 4, insulin-responsive
- Glucose transporter type 4
- insulin-responsive
背景信息 The protein called GLUT-4, or more correctly Solute carrier family 2, facilitated glucose transporter member 4 and encoded by the human gene SLC2A4/GLUT4 is a primary insulin regulated facilitative glucose transporter found primarily in skeletal and cardiac muscle, as well as brown and white fat but is also expressed in other tissues such as brain. In the brain GLUT4 is found exclusively in neurons. GLUT-4 is facilitative because it is not always present on the cell plasma membrane. GLUT-4 only localizes to the plasma membrane upon insulin induction. GLUT-4 is localized to the perinuclear region in resting cells. Mutations in GLUT-4 are a cause of one form of non-insulin dependent diabetes mellitus. GLUT4 function as well as its transcriptional regulation is highly conserved throughout the vertebrate species. 产品信息 格式 Affinity Purified 控制 - NIH3T3 cell lysate
演示 Purified rabbit polyclonal in buffer containing PBS with 0.05% sodium azide. 应用 应用 Detect GLUT-4 using this Anti-GLUT-4 Antibody, C-terminus validated for use in WB, IH(P), ELISA. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:50-2,000 dilution from a representative lot detected GLUT-4 in human cardiac myocytes and human skeletal muscle myocytes. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to the C-terminus of human GLUT-4. 表位 C-terminus 宿主 Rabbit 特异性 Glucose transporter 4 (GLUT-4) is a protein present in rat skeletal muscle, heart and adipose tissues. GLUT-4 is highly conserved between species, and the peptide sequence selected for production of this antibody is identical in rat, human (amino acids 498-510), and mouse. This antibody shows no cross-reactivity of HepG2 type transporter from rat brain or other glucose transporters.
品种反应性 MouseHuman Species Reactivity Note Human, Mouse. Predicted to react with Rat based on 100% sequence homology. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_001033
基因符号 - GLUT4
- SLC2A4
- GLUT-4
纯化方法 Affinity Purfied UniProt编号 - P14672
产品使用声明 质量保证 Evaluated by Western Blotting in NIH3T3 cell lysate.
Western Blotting Analysis: A 1:1,000 dilution of this antibody detected GLUT-4 in 10 µg of NIH3T3 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µL
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下一件merck millipore产品：merck millipore,默克密理博,FCMAB420F,Milli-Mark Anti-PKCα-FITC Antibody, clone M4
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