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品种反应性 主要应用 宿主 格式 抗体类型 R, B, H, M ICC, WB Rb Purified Polyclonal Antibody 描述 产品目录编号 06-566 品牌系列 Upstate
商名 - Upstate
描述 Anti-Csk Antibody 产品信息 格式 Purified 演示 of 0.1M Tris-glycine, pH 7.4, 0.15M NaCl with 0.05% sodium azide 应用 应用 This Anti-Csk Antibody is validated for use in WB, IC for the detection of Csk. 主要应用 - Immunocytochemistry
- Western Blotting
生物信息 免疫原品种 BSA linked synthetic peptide corresponding to amino acid residues 422-450 (CWHLDAATRPTFLQLREQLEHIRTHELHL) of rat Csk 宿主 Rabbit 特异性 Csk 同种型 IgG 品种反应性 RatBovineHumanMouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_007783
基因符号 - MGC117393
- CSK
纯化方法 Protein A chromatography UniProt编号 - P41240
UniProt汇总 FUNCTION: SwissProt: P41240 # Specifically phosphorylates 'Tyr-504' on LCK, which acts as a negative regulatory site. Can also act on the LYN and FYN kinases.
SIZE: 450 amino acids; 50704 Da
SUBUNIT: Interacts with PTPN8 (By similarity). Interacts with phosphorylated SIT1, PAG1, LIME1 and TGFB1I1.
SUBCELLULAR LOCATION: Cytoplasm (By similarity). Cell membrane (By similarity). Note=Mainly cytoplasmic, also present in lipid rafts (By similarity).
TISSUE SPECIFICITY: Expressed in lung and macrophages.
PTM: Autophosphorylation of Tyr-304 occurs only at abnormally high CSK concentrations in vitro.
SIMILARITY: SwissProt: P41240 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily. & Contains 1 protein kinase domain. & Contains 1 SH2 domain. & Contains 1 SH3 domain.产品使用声明 质量保证 routinely evaluated by immunoblot on lysates from TF-1 cells 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C 包装信息 数量 200 µg
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