merck millipore,默克密理愽
  • merck millipore,默克密理博,14-462,Rsk3 Protein, active, 10 µg

  • merck millipore,默克密理博,14-462,Rsk3 Protein, active, 10 µg

    产品名称：Rsk3 Protein, active, 10 µg
    产品型号：14-462
    Active, N-terminal His6-tagged recombinant full-length, human RSK3, for use in Kinase Assays.

    merck millipore,默克密理博,14-462,Rsk3 Protein, active, 10 µg

  • 产品介绍
  • merck millipore,默克密理博,14-462,Rsk3 Protein, active, 10 µg

    描述
    产品目录编号 14-462
    品牌系列 Upstate
    商名
    • Upstate
    描述 Rsk3 Protein, active, 10 µg
    概述 N-terminal His6-tagged recombinant full-length, human RSK3
    应用
    应用 Active, N-terminal His6-tagged recombinant full-length, human RSK3, for use in Kinase Assays.
    主要应用
    • Kinase Assay
    生物信息
    来源 expressed in Sf21 insect cells
    品种 Human
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
    Entrez基因编号
    • NM_021135.4
    • NM_001006932.1
    Entrez基因汇总 This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
    基因符号
    • p90-RSK3
    • RPS6KA2
    • S6K-alpha
    • RSK-3
    • MAPKAPK1C
    • RSK3
    • S6K-alpha2
    • pp90RSK3
    • HU-2
    • RSK
    蛋白靶 Rsk3
    纯化方法 Ni2+/NTA-agarose
    靶子系列 AGC
    UniProt编号
    • Q15349
    UniProt汇总 FUNCTION: SwissProt: Q15349 # Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.
    COFACTOR: Magnesium.
    SIZE: 733 amino acids; 83239 Da
    SUBUNIT: Forms a complex with either ERK1 or ERK2 in quiescent cells. Transiently dissociates following mitogenic stimulation (By similarity).
    SUBCELLULAR LOCATION: Nucleus.
    TISSUE SPECIFICITY: Expressed in many tissues. Highest expression in lung and skeletal muscle.
    PTM: Autophosphorylated on Ser-377, as part of the activation process (By similarity).
    SIMILARITY: SwissProt: Q15349 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 2 protein kinase domains.
    产品使用声明
    质量保证 routinely evaluated by phosphorylation of the MAPKAP Kinase 2 substrate peptide
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 1 year at -70°C
    包装信息
    数量 10 µg
    包装 Also available in 250 µg size --call for pricing and availability and reference catalog number 14-462M when ordering the 250 µg size.

    merck millipore,默克密理博,14-462,Rsk3 Protein, active, 10 µg

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