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品种反应性 主要应用 宿主 格式 抗体类型 M, H WB Rb Purified Polyclonal Antibody 描述 产品目录编号 06-546 品牌系列 Upstate
商名 - Upstate
描述 Anti-Itk/Emt/Tsk Antibody 产品信息 格式 Purified 演示 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30% 应用 应用 This Anti-Itk/Emt/Tsk Antibody is validated for use in IP, WB for the detection of Itk/Emt/Tsk. 主要应用 - Western Blotting
生物信息 免疫原品种 Itk/Emt/Tsk-GST fusion protein (Itk/Emt/Tsk amino acid residues 1-270) spanning the PH, SH3 domains and a small portion of the SH2 domain 宿主 Rabbit 特异性 Itk/Emt/Tsk 同种型 IgG 品种反应性 MouseHuman 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_005546
Entrez基因汇总 This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. 基因符号 - MGC126257
- ITK
- LYK
- PSCTK2
- EMT
- MGC126258
纯化方法 Protein A chromatography UniProt编号 - Q08881
UniProt汇总 FUNCTION: SwissProt: Q08881 # Plays a role in T-cell proliferation and differentiation.
COFACTOR: Binds 1 zinc ion per subunit (By similarity).
SIZE: 620 amino acids; 71831 Da
SUBCELLULAR LOCATION: Cell membrane (By similarity). Note=Localizes to cell surface receptors in the plasma membrane after stimulation with respective receptors (TCR, CD28, CD2) in T- cells (By similarity).
TISSUE SPECIFICITY: T-cell lines and natural killer cell lines.
SIMILARITY: SwissProt: Q08881 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. TEC subfamily. & Contains 1 Btk-type zinc finger. & Contains 1 PH domain. & Contains 1 protein kinase domain. & Contains 1 SH2 domain. & Contains 1 SH3 domain.产品使用声明 质量保证 routinely evaluated by immunoblot on Jurkat cell RIPA lysate 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C 包装信息 数量 250 µg
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