merck millipore,默克密理愽
  • merck millipore,默克密理博,06-1115,Anti-Interleukin-18 (IL-18) Antibody

  • merck millipore,默克密理博,06-1115,Anti-Interleukin-18 (IL-18) Antibody

    产品名称：Anti-Interleukin-18 (IL-18) Antibody
    产品型号：06-1115
    This Anti-Interleukin-18 (IL-18) Antibody is validated for use in WB, IH(P) for the detection of Interleukin-18 (IL-18).

    merck millipore,默克密理博,06-1115,Anti-Interleukin-18 (IL-18) Antibody

  • 产品介绍
  • merck millipore,默克密理博,06-1115,Anti-Interleukin-18 (IL-18) Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    Pm, H, Chp, Rhesus MacaqueWBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 06-1115
    描述 Anti-Interleukin-18 (IL-18) Antibody
    Alternate Names
    • Interferon gamma-inducing factor
    • interleukin 18 (interferon-gamma-inducing factor)
    • IL-1 gamma
    • IFN-gamma-inducing factor
    • iboctadekin
    • interleukin-18
    • Interleukin-1 gamma
    • Iboctadekin
    背景信息 IL-18 has been shown to be a pro-inflammatory cytokine that induces interferon-gamma. IL-18 has also been found to have the ability to activate nuclear factor-kappaB (NFkB), express Fas ligand, induce CC and CXC chemokines, and also has been found to increase the production of viable human immunodeficiency virus. IL-18 has been linked to syndromes displaying symptoms of chronic low-levels of inflammation. IL-18 also seems to have some control over homeostasis and behavior in the central nervous system as well as neuroinflammatory activity.
    产品信息
    格式 Affinity Purified
    控制
    • Human tonsil tissue lysate
    演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 This Anti-Interleukin-18 (IL-18) Antibody is validated for use in WB, IH(P) for the detection of Interleukin-18 (IL-18).
    主要应用
    • Western Blotting
    应用说明 Western Blot (Snap i.d.) Analysis: 5 µg/mL from a previous lot detected IL-18 in 10 µg of human tonsil tissue lysate.

    Immunohistochemistry Analysis: A 1:600 dilution from a previous lot detected IL-18 in normal human spleen tissue.
    生物信息
    免疫原品种 KLH-conjugated linear peptide corresponding to human Interleukin-18.
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    品种反应性 PrimateHumanChimpanzeeRhesus Macaque
    Species Reactivity Note Demonstrated to react with human.
    Predicted to react with chimpanzee, rhesus macaque, and primate based on 100% sequence homology.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NP_001553
    Entrez基因汇总 The protein encoded by this gene is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. [provided by RefSeq].
    基因符号
    • IL-1g
    • IL-18
    • IL18
    • IGIF
    • IL1F4
    纯化方法 Affinity Purified
    UniProt编号
    • Q14116
    UniProt汇总 FUNCTION: Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells.

    SUBCELLULAR LOCATION: Secreted.

    SEQUENCE SIMILARITIES: Belongs to the IL-1 family.
    产品使用声明
    质量保证 Evaluated by Western Blot in human tonsil tissue lysate.

    Western Blot Analysis: 0.5 µg/mL of this antibody detected IL-18 in 10 µg of human tonsil tissue lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,06-1115,Anti-Interleukin-18 (IL-18) Antibody

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