merck millipore,默克密理博,06-1064,Anti-Itk/Emt/Tsk Antibody

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merck millipore,默克密理博,06-1064,Anti-Itk/Emt/Tsk Antibody
产品名称：Anti-Itk/Emt/Tsk Antibody
产品型号：06-1064
Detect Itk/Emt/Tsk using this Anti-Itk/Emt/Tsk Antibody validated for use in WB & IP.

merck millipore,默克密理博,06-1064,Anti-Itk/Emt/Tsk Antibody

产品介绍

merck millipore,默克密理博,06-1064,Anti-Itk/Emt/Tsk Antibody

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
M, H	WB	Rb	Affinity Purified	Polyclonal Antibody

描述
产品目录编号	06-1064
Replaces	06-546
描述	Anti-Itk/Emt/Tsk Antibody
Alternate Names	tyrosine-protein kinase ITK/TSK IL2-inducible T-cell kinase Kinase EMT T-cell-specific kinase Tyrosine-protein kinase Lyk homolog of mouse T-cell itk/tsk
背景信息	Itk is a T cell signaling protein. The Tec family of non-receptor tyrosine kinases is composed of six proteins designated Tec, Itk (also known as Emt or Tsk), Btk (previously known as Atk, BPK or Emb), Bmx, Txk (also known as Rlk) and Dsrc28C. All members of the family contain SH3 and SH2 domains and, with the exception of Txk and Dsrc28C, also contain pleckstrin homology (PH) and Tec homology (TH) domains in their amino termini. Itk associates with CD28 and becomes activated subsequent to CD28 ligation.

产品信息
格式	Affinity Purified
控制	Jurkat cell lysates
演示	Purified rabbit polycloncal in buffer containing PBS with 0.05% sodium azide and 50% glycerol.

应用
应用	Detect Itk/Emt/Tsk using this Anti-Itk/Emt/Tsk Antibody validated for use in WB & IP.
主要应用	Western Blotting

生物信息
免疫原品种	Recombinant protein. Itk/Emt/Tsk-GST fusion protein (Itk/Emt/Tsk amino acid residues 1-270) spanning the PH, SH3 domains and a small portion of the SH2 domain; bound to nitrocellulose paper.
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Rabbit
特异性	Recognizes Itk/Emt/Tsk, Mr ~72 kDa.
品种反应性	MouseHuman
Species Reactivity Note	Human. Predicted to cross-react with mouse based on 100% sequence homology.
抗体类型	Polyclonal Antibody
Entrez基因编号	NP_005537
Entrez基因汇总	This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. [provided by RefSeq]
基因符号	PSCTK2 EC 2.7.10.2 EMT LYK MGC126257 MGC126258
纯化方法	Affinity Purfied
UniProt编号	Q08881

产品使用声明
质量保证	Routinely evaluated by western blot on Jurkat cell lysate. Western Blot Analysis: 0.05-1 µg/mL of this lot detected Itk/Emt/Tsk in 10 µg of a Jurkat cell lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. For maximum recovery of the product, centrifuge the original vial and prior to removing the cap. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol-containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt. For maximum recovery of the product, centrifuge the original vial and prior to removing the cap. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol-containing solutions to become frozen during storage.