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品种反应性 主要应用 宿主 格式 抗体类型 H, B WB M Ascites Monoclonal Antibody 描述 产品目录编号 05-337 品牌系列 Upstate
商名 - Upstate
描述 Anti-MARCKS Antibody, clone 2F12 产品信息 格式 Ascites 演示 mouse ascites containing 0.05% sodium azide 应用 应用 Anti-MARCKS Antibody, clone 2F12 detects level of MARCKS & has been published & validated for use in IP & WB. 主要应用 - Western Blotting
生物信息 免疫原品种 Purified recombinant human MARCKS; Epitope mapped to the carboxyl-terminal. 克隆 2F12 宿主 Mouse 特异性 MARCKS 同种型 IgG1 品种反应性 HumanBovine 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_002356
Entrez基因汇总 The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. 基因符号 - FLJ90045
- MARCKS
- 80K-L
- MACS
- PRKCSL
- FLJ14368
- phosphomyristin
- MRACKS
- PKCSL
纯化方法 Ascites UniProt编号 - P29966
UniProt汇总 FUNCTION: SwissProt: P29966 # MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F) actin cross-linking protein.
SIZE: 332 amino acids; 31555 Da
PTM: Phosphorylation by PKC displaces MARCKS from the membrane. It also inhibits the F-actin cross-linking activity.
SIMILARITY: SwissProt: P29966 ## Belongs to the MARCKS family.产品使用声明 质量保证 routinely evaluated by immunoblot on bovine brain extract 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 6 months at -20°C 包装信息 数量 200 µL
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