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merck millipore,默克密理博,MABS71,Anti-phospho-MAPK 1/2 (Thr203/Ty205) Antibody, clone 14B9.1
产品名称：Anti-phospho-MAPK 1/2 (Thr203/Ty205) Antibody, clone 14B9.1
产品型号：MABS71
Anti-phospho-MAPK 1/2 (Thr203/Ty205) Antibody, clone 14B9.1 is a highly specific mouse monoclonal antibody & that targets MAPK/Erk1/2 & has been tested in western blotting.
merck millipore,默克密理博,MABS71,Anti-phospho-MAPK 1/2 (Thr203/Ty205) Antibody, clone 14B9.1
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB M Purified Monoclonal Antibody 描述 产品目录编号 MABS71 Replaces 05-481 描述 Anti-phospho-MAPK 1/2 (Thr203/Ty205) Antibody, clone 14B9.1 Alternate Names - p44-ERK1
- Mitogen-activated protein kinase 3
- MAP kinase 3
- MAPK 3
- ERT2
- Extracellular signal-regulated kinase 1
- ERK-1
- Insulin-stimulated MAP2 kinase
- MAP kinase isoform p44
- p44-MAPK
- Microtubule-associated protein 2 kinase
背景信息 The extracellular signal-regulated kinases 1 and 2 (ERK1 and ERK2), also called p44 and p42 MAP kinases, are members of the Mitogen Activated Protein Kinase (MAPK) family of proteins found in all eukaryotes. The 44 kDa ERK1 and the 42 kDa ERK2 are highly homologous and both function in the same protein kinase cascade. For this reason, the two proteins are often referred to collectively as ERK1/2 or p44/p42 MAP kinase. The ERK1/2 signaling cascade has been shown to be a critical regulator of cell differentiation, cell physiology and neuronal function. Aberrant control of ERK1/2 activity has been implicated in a variety of pathological conditions, including cancer and autoimmune diseases, and efficient study methods are in demand. Extracellular signal/mitogen activated protein kinases (erk/MAPK) are a group of proline-directed serine/threonine kinases that are activated by dual phosphorylation of conserved threonine and tyrosine residues within a characteristic T X Y peptide motif. The mitogen-activated kinases erk1 (MAPK1) and erk2 (MAPK2) acquire full enzymatic activity upon phosphorylation of both threonine and tyrosine residues within the sequence motif T E Y. 产品信息 格式 Purified 控制 - A431cell lysate and EGF treated A431 cell lysate
演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-phospho-MAPK 1/2 (Thr203/Ty205) Antibody, clone 14B9.1 is a highly specific mouse monoclonal antibody & that targets MAPK/Erk1/2 & has been tested in western blotting. 主要应用 - Western Blotting
生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human MAPK 1/2 phosphorylated at Thr203 and Ty205. 克隆 14B9.1 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 Antibody recognizes dual phosphorylation of MAPK1/2 at Thr203/Tyr204, but this antibody has not been used for the detection of single phosphorylation at either site. 同种型 IgG1κ 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_001035145
基因符号 - PRKM3
- MAPK3
- ERK1
纯化方法 Protein G purified UniProt编号 - P27361
产品使用声明 质量保证 Evaluated by Western Blotting in A431 cell lysate.
Western Blotting Analysis: 0.1 µg/mL of this antibody detected phospho-MAPK 1/2 (Thr203/Ty205) in 200 µg of A431cell lysate and EGF treated A431 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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