merck millipore,默克密理博,05-23-0600,Substance P - CAS 33507-63-0

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merck millipore,默克密理博,05-23-0600,Substance P - CAS 33507-63-0 - Calbiochem
产品名称：Substance P - CAS 33507-63-0 - Calbiochem
产品型号：05-23-0600
Neuropeptide found in high concentrations in the gut.

merck millipore,默克密理博,05-23-0600,Substance P - CAS 33507-63-0 - Calbiochem

产品介绍

merck millipore,默克密理博,05-23-0600,Substance P - CAS 33507-63-0 - Calbiochem

重要规格表

经验配方	CAS号
C₆₃H₉₈N₁₈O₁₃S	33507-63-0

描述
概述	Neuropeptide found in high concentrations in the gut. When released from afferent nerves, causes a neurogenic inflammatory response, including mast cell degranulation. Induces Ca²⁺ mobilization. Reported to activate G_oα, G_q/11α, and G_sα subunits in CHO cells via activation of substance P receptors. Also reported to induce superoxide production in neutrophils.
产品目录编号	05-23-0600
品牌系列	Calbiochem®
同义词	RPKPQQFFGLM

参考
参考	Roush, E.D., and Kwatra, M.M. 1998. FEBS Lett. 428, 291. Chiwakata, C.B., et al. 1996. Infect. Immun. 64, 5106. Tanabe, T., et al. 1996. Eur. J. Pharmacol. 299, 187. Heath, M.J., et al. 1994. J. Neurophysiol. 72, 1192. Zhu, J., et al. 1994. Eur. J. Pharmacol. 268, 279. Garland, A.M., et al. 1993. Soc. Neurosci. 19, Abstract 104.6. Wei, J.Y., et al. 1993. Soc. Neurosci. 19, Abstract 136.14.

参考

Roush, E.D., and Kwatra, M.M. 1998. FEBS Lett. 428, 291.
Chiwakata, C.B., et al. 1996. Infect. Immun. 64, 5106.
Tanabe, T., et al. 1996. Eur. J. Pharmacol. 299, 187.
Heath, M.J., et al. 1994. J. Neurophysiol. 72, 1192.
Zhu, J., et al. 1994. Eur. J. Pharmacol. 268, 279.
Garland, A.M., et al. 1993. Soc. Neurosci. 19, Abstract 104.6.
Wei, J.Y., et al. 1993. Soc. Neurosci. 19, Abstract 136.14.

产品信息
CAS号	33507-63-0
具有ATP竞争性	N
形式	White solid
配方	Supplied as a trifluoroacetate salt.
Hill配方	C₆₃H₉₈N₁₈O₁₃S
化学配方	C₆₃H₉₈N₁₈O₁₃S
Molar Mass	1347.6
吸湿	Hygroscopic
肽序列	H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH₂
可逆	N
基于肽含量售出	Yes

生物信息
主靶	Substance P receptors
纯度	≥96% by HPLC

理化信息
细胞可渗透	N
溶解度	5% Acetic Acid
肽含量	Yes
肽序列	H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH₂

储存和货运信息
货运代码	Ambient Temperature Only
毒性	Standard Handling
储存	-20°C
吸湿	Hygroscopic
无需冷冻	No
特殊指南	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.