merck millipore,默克密理愽
  • merck millipore,默克密理博,MABN611,Anti-Lgi1 Antibody, clone N283/7

  • merck millipore,默克密理博,MABN611,Anti-Lgi1 Antibody, clone N283/7

    产品名称：Anti-Lgi1 Antibody, clone N283/7
    产品型号：MABN611
    Anti-Lgi1 Antibody, clone N283/7 is a highly specific mouse monoclonal antibody, that targets LGI1 & has been tested in western blotting & IHC.

    merck millipore,默克密理博,MABN611,Anti-Lgi1 Antibody, clone N283/7

  • 产品介绍
  • merck millipore,默克密理博,MABN611,Anti-Lgi1 Antibody, clone N283/7

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, MIHC, WBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABN611
    描述 Anti-Lgi1 Antibody, clone N283/7
    Alternate Names
    • Leucine-rich glioma-inactivated protein 1
    背景信息 The Leucine-rich, glioma inactivated gene 1 (LGI1) was first identified as tumor suppressor gene for glioma and may play a role in other cancers. LGI1 is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) which are very similar to other transmembrane signaling molecules and receptors. LGI1 serves as a ligand to ADAM22, a metalloprotease localized at the synapse. Mutations in LGI1 account for nearly half of autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms.
    产品信息
    格式 Purified
    控制
    • Mouse brain membrane tissue
    演示 Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Anti-Lgi1 Antibody, clone N283/7 is a highly specific mouse monoclonal antibody, that targets LGI1 & has been tested in western blotting & IHC.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    应用说明 Western Blotting Analysis: A representative lot detected Lgi1 in whole brain homogenates from wild type (WT) mice, and demonstrated a loss of signal in whole brain homogenates from Lgi1 knockout (KO) mice (Prof. J. Trimmer, University of California, Davis.).

    Immunohistochemistry Analysis: A representative lot detected Lgi1 in rat brain hippocampus tissue prepared without citrate treatment, and with citrate treatment for antigen retrieval (Prof. J. Trimmer, University of California, Davis.).
    生物信息
    免疫原品种 Recombinant, truncated protein corresponding to mouse Lgi1.
    克隆 N283/7
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 This antibody does not cross react with Lgi2, Lgi3, and Lgi4 (Prof. J. Trimmer, University of California, Davis.).
    同种型 IgG2aκ
    品种反应性 RatMouse
    Species Reactivity Note Demonstrated to react with Mouse and Rat. Other homologies: Human (98% sequence homology)
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_064674
    基因符号
    • Lgi1
    纯化方法 Protein G purified
    UniProt编号
    • Q9JIA1
    产品使用声明
    质量保证 Evaluated by Western Blotting in mouse brain membrane tissue.

    Western Blotting Analysis: 4 µg/mL of this antibody detected Lgi1 in 10 µg of mouse brain membrane tissue.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MABN611,Anti-Lgi1 Antibody, clone N283/7

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