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merck millipore,默克密理博,04-048,Anti-MBNL Antibody, clone 3A4
产品名称：Anti-MBNL Antibody, clone 3A4
产品型号：04-048
Anti-MBNL Antibody, clone 3A4 is a Mouse Monoclonal Antibody for detection of MBNL also known as Muscleblind-like protein 1, Triplet-expansion RNA-binding protein & has been validated in WB.
merck millipore,默克密理博,04-048,Anti-MBNL Antibody, clone 3A4
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB M Ascites Monoclonal Antibody 描述 产品目录编号 04-048 品牌系列 Upstate
商名 - Upstate
描述 Anti-MBNL Antibody, clone 3A4 Alternate Names - Muscleblind-like protein 1
- muscleblind-like (Drosophila)
- Triplet-expansion RNA-binding protein
- DKFZp686P06174
- KIAA0428
- EXP35
- EXP42
- EXP40
背景信息 Myotonic dystrophy (DM1) is a neuromuscular disorder associated with repeated CTG triplets in the 3'-untranslated region of the DMPK gene. It is hypothesized that the CUG repeats in the mRNA form hairpins that sequester nuclear factors required for proper muscle development and maintenance. MBNL (muscleblind-like protein 1) is an RNA splicing factor that binds to the CUG repeats and is enriched at these mutant RNA foci. MBNL-deficient mice are often used as a model for myotonic muscular dystrophy and siRNA downregulation of MBNL in normal myoblasts results in abnormal insulin receptor splicing. 产品信息 格式 Ascites 控制 - Jurkat cell lysate
演示 Mouse ascites IgG1 in buffer containing 0.05% sodium azide. 应用 应用 Anti-MBNL Antibody, clone 3A4 is a Mouse Monoclonal Antibody for detection of MBNL also known as Muscleblind-like protein 1, Triplet-expansion RNA-binding protein & has been validated in WB. 主要应用 - Western Blotting
应用说明 Western Blot Analysis: A 1:1000 dilution of this lot detected MBNL-1 on Jurkat cell lysate. Optimal working dilutions must be determined by the end user. 生物信息 免疫原品种 Recombinant MBNL-1 41 kDa isoform amino acids 116-182 表位 a.a. 116-182 克隆 clone 3A4 宿主 Mouse 特异性 Antibody recognizes MBNL-1 同种型 IgG1 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_778225
基因符号 - GC03P153468
纯化方法 Ascites UniProt编号 - Q9NR56
产品使用声明 质量保证 Routinely evaluated by western blot on Jurkat cell lysate. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. 包装信息 数量 100 µL
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