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主要应用 品种 EA Human 描述 产品目录编号 03-188 品牌系列 Upstate
商名 - Upstate
描述 p300 (catalytic domain) human recombinant 概述 Human recombinant p300 (catalytic domain) expressed in E. Coli 背景信息 Although originally termed histone acetyltransferases (HATs) for their lysine acetylation activity on histone N-terminal tails, p300 and its paralogue, CBP, have been shown to acetylate a variety of non-histone proteins including p53, DNA polymerase ß and nuclear import factors. p300/CBP acetylations play regulatory roles in transcription, DNA repair and replication, the cell cycle, p53 turnover, and nuclear import. In addition to functions which overlap with those of CBP, p300 has a number of unique functions, including a role in the induction of p21Waf1/Cip1 cell cycle inhibitor. 产品信息 格式 Purified 演示 In liquid containing 50 mM Tris/HCl, pH 8.0, 0.1 mM EDTA, 10% glycerol 应用 应用 Human recombinant p300 (catalytic domain) expressed in E. Coli. 主要应用 - Enzyme Assay
应用说明 Acetyltransferase assays 生物信息 宿主 E. coli 纯度 Purity >75% by SDS-PAGE 来源 Catalytic domain of huma p300 品种 Human 特异活性 >250 pmol/min/µg assayed as production of CoA-SH from AcCoA in the presence of a peptide comprising human p53 residues 368-386. CoA-SH is determined colorimetrically by reaction with DTNB (5,5′-Dithiobis (2-nitrobenzoic acid). 物理形式 Frozen solution 产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 12 months at -80ºC from date of receipt. Avoid multiple freeze/thaw cycles. 包装信息 数量 100 µg
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下一件merck millipore产品：merck millipore,默克密理博,219007,Caspase Inhibitor VI - CAS 161401-82-7 - Calbiochem
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