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主要应用 品种 来源 CULT Human Recombinant Human Interferon-gamma 描述 产品目录编号 01-172 品牌系列 Upstate
商名 - Upstate
描述 Interferon-gamma (IFNγ) 产品信息 演示 Lyophilized from PBS, pH 7.4 应用 应用 This Interferon-gamma (IFNγ) protein is available in a 100 µg format. 主要应用 - Cell Culture
生物信息 来源 Recombinant Human Interferon-gamma 品种 Human Entrez基因编号 - NM_000619.2
基因符号 - IFG
- IFNG
- IFN-gamma
- IFI
物理形式 Lyophilized 纯化方法 Sterilized through a 0.2 micron membrane filter UniProt编号 - P01579
UniProt汇总 FUNCTION: SwissProt: P01579 # Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
SIZE: 166 amino acids; 19348 Da
SUBUNIT: Homodimer.
SUBCELLULAR LOCATION: Secreted.
TISSUE SPECIFICITY: Released primarily from activated T lymphocytes.
PTM: Proteolytic processing produces C-terminal heterogeneity, with proteins ending alternatively at Gly-150, Met-157 or Gly-161.
DISEASE: SwissProt: P01579 # In Caucasians, genetic variation in IFNG is associated with the risk of aplastic anemia (AA) [MIM:609135]. AA is a rare disease in which the reduction of the circulating blood cells results from damage to the stem cell pool in bone marrow. In most patients, the stem cell lesion is caused by an autoimmune attack. T-lymphocytes, activated by an endogenous or exogenous, and most often unknown antigenic stimulus, secrete cytokines, including IFN-gamma, which would in turn be able to suppress hematopoiesis.
SIMILARITY: SwissProt: P01579 ## Belongs to the type II (or gamma) interferon family.产品使用声明 质量保证 Routinely evaluated in a biological activity assay. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
包装信息 数量 100 µg
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