merck millipore,默克密理愽
  • merck millipore,默克密理博,SF-126,GAPDH; Human, Cyanine 3, RNA Detection Probe,SmartFlare

  • merck millipore,默克密理博,SF-126,GAPDH; Human, Cyanine 3, RNA Detection Probe,SmartFlare

    产品名称：GAPDH; Human, Cyanine 3, RNA Detection Probe, SmartFlare
    产品型号：SF-126
    SmartFlare GAPDH; Human, Cyanine 3 is a RNA Detection probe that targets the GAPDH housekeeping gene. Use SmartFlare housekeeping controls as a proof of concept for your gene expression experiments or More>>

    merck millipore,默克密理博,SF-126,GAPDH; Human, Cyanine 3, RNA Detection Probe,SmartFlare

  • 产品介绍
  • merck millipore,默克密理博,SF-126,GAPDH; Human, Cyanine 3, RNA Detection Probe,SmartFlare

    重要规格表

    Entrez Gene Number Species Reactivity Species Reactivity Note
    NM_001256799.1HNM_002046.4
    描述
    产品目录编号 SF-126
    商名
    • SmartFlare
    描述 GAPDH; Human, Cyanine 3, RNA Detection Probe | SmartFlare
    背景信息 GAPDH; Human, Cyanine 3, RNA Detection Probe is a RNA Detection probe that targets the GAPDH housekeeping gene. Use SmartFlare housekeeping controls as a proof of concept for your gene expression experiments or as a positive control for more advanced gene modulation experiments.
    Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is an ubiquitous glycolytic enzyme present in moderately high levels in almost all tissues. As a 'house-keeping' enzyme, it catalyzes the synthesis of 1,3-biphosphoglycerate, a "high energy" intermediate used for the synthesis of ATP. Besides its cytoplasmic action in metabolism it is also involved in the initial stages of apoptosis or oxidative stress response where GAPDH is translocated to the nucleus. Such actions may reflect the role of GAPDH in DNA repair or as one nuclear carrier for apoptotic molecules. GAPDH has also been found to bind specifically to proteins implicated in the pathogenesis of a variety of neurodegenerative disorders including the beta-amyloid precursor protein and the huntingtin protein where decreased function of GAPDH is associated with Alzheimer's and Huntington's disease fibroblasts. GAPDH has also been identified as a potential target for nitric oxide (NO)-mediated cellular toxicity. The complete and functional enzyme is a tetramer with each of four identical subunits occupying the vertex of a tetrahedron. Binding domains also include one principally interacting with NAD+ and another interacting with glyceraldehyde 3-phosphate (GAP).
    产品信息
    格式 Cyanine 3
    演示 Lyophilized
    应用
    应用 SmartFlare GAPDH; Human, Cyanine 3 is a RNA Detection probe that targets the GAPDH housekeeping gene. Use SmartFlare housekeeping controls as a proof of concept for your gene expression experiments or as a positive control for gene modulation experiments.
    主要应用
    • RNA Detection
    生物信息
    品种反应性 Human
    Species Reactivity Note NM_002046.4
    Entrez基因编号
    • NM_001256799.1
    基因符号
    • GAPDH
    产品使用声明
    质量保证 SmartFlare Probes have been tested in a buffer system to detect the release of the fluorophore in the presence of a complimentary base pair sequence for each lot to confirm target specificity. SmartFlare Probes have also been tested in a cell model system and demonstrated increased fluorescence in cells expressing the target compared to a negative SmartFlare Scramble Control.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Store at 2–8°C in lyophilized format ONLY. Room temperature is required for reconstituted product.
    包装信息
    数量 250 reactions

    merck millipore,默克密理博,SF-126,GAPDH; Human, Cyanine 3, RNA Detection Probe,SmartFlare

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