- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
-
-
merck millipore,默克密理博,SF-1191,LRRK2; Human, Cyanine 5 RNA Detection Probe,SmartFlare
产品名称：LRRK2; Human, Cyanine 5 RNA Detection Probe, SmartFlare
产品型号：SF-1191
Use SmartFlare RNA Detection probes to measure gene expression in live cells. With an overnight incubation of SmartFlare LRRK2, Human, Cyanine 5, you can detect LRRK2 RNA levels within your cells.
merck millipore,默克密理博,SF-1191,LRRK2; Human, Cyanine 5 RNA Detection Probe,SmartFlare
- 产品介绍
重要规格表
Entrez Gene Number Species Reactivity NM_198578.3 H 描述 产品目录编号 SF-1191 商名 - SmartFlare
描述 LRRK2; Human, Cyanine 5 RNA Detection Probe | SmartFlare Alternate Names - ROCO2
- PARK8
- RIPK7
背景信息 With SmartFlare™ RNA Detection probes, you can detect RNA in LIVE CELLS with ease. With just an overnight incubation of LRRK2; Human, Cyanine 5 RNA Detection Probe you can detect the presence of LRRK2 within your cells.
LRRK2 (Leucine-rich repeat serine/threonine-protein kinase 2) is a multifunctional protein belonging to the ROCO family of proteins. LRRK2 contains multiple domains including a ROC (Ras of Complex protein) domain that binds and hydrolyzes GTP, and a kinase domain involved in the phosphorylation of myelin basic protein (MBP), mosein, ezrin, and radixin. LRRK2 itself undergoes autophosphorylation and is targeted by other kinases that modify multiple serine residues at its N-terminus; It is constitutively phosphorylated at Ser935 and maintains this state by interaction with the 14-3-3 protein. Although the kinases upstream of LRRK2 have not been definitively identified, previous studies have suggested that this group of kinases may include PKA. It also contains multiple leucine-rich repeat motifs that facilitate interaction with a range of proteins including PARK2 and PRDX3. Mutations in LRRK2, most of which have enhanced its kinase activity, may contribute to the development of late-onset familial Parkinson’s disease; however, the precise molecular mechanism of LRRK2-induced Parkinson’s disease is still unclear.产品信息 格式 Cyanine 5 演示 Lyophilized 应用 应用 Use SmartFlare RNA Detection probes to measure gene expression in live cells. With an overnight incubation of SmartFlare LRRK2, Human, Cyanine 5, you can detect LRRK2 RNA levels within your cells. 主要应用 - RNA Detection
生物信息 品种反应性 Human Entrez基因编号 - NM_198578.3
基因符号 - LRRK2
产品使用声明 质量保证 SmartFlare Probes have been tested in a buffer system to detect the release of the fluorophore in the presence of a complimentary base pair sequence for each lot to confirm target specificity. SmartFlare Probes have also been tested in a cell model system and demonstrated increased fluorescence in cells expressing the target compared to a negative SmartFlare Scramble Control. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Store at 2–8°C in lyophilized format ONLY. Room temperature is required for reconstituted product. 包装信息 数量 250 reactions
上一件merck millipore产品：merck millipore,默克密理博,ABE391,Anti-RPS3 Antibody
下一件merck millipore产品：merck millipore,默克密理博,MAB10765,Anti-Red Fluorescent Protein Antibody, clone 1DS-1A6,MAB10765
相关产品
merck millipore,默克密理博,567735,Sphingosylphosphoryl-choline - CAS 1670-26-4 - Calbiochem
merck millipore,默克密理博,04-211,Anti-c-Jun (NT) Antibody, clone E254, rabbit monoclonal
merck millipore,默克密理博,05-1338-S,Anti-Dimethyl Histone H3 (Lys4) Antibody, clone CMA303, Trial Size
merck millipore,默克密理博,LSKS09601,测序反应物纯化试剂盒96
merck millipore,默克密理博,ABE391,Anti-RPS3 Antibody
merck millipore,默克密理博,MAB10765,Anti-Red Fluorescent Protein Antibody, clone 1DS-1A6,MAB10765
merck millipore,默克密理博,05-1341,Anti-Histone H3 Antibody, (Unmodified Lys4), clone CMA301
merck millipore,默克密理博,529573,PP2 - CAS 172889-27-9 - Calbiochem
merck millipore,默克密理博,218696,Casein Kinase I Inhibitor, D4476 - CAS 301836-43-1 - Calbiochem
