• merck millipore,默克密理博,567735,Sphingosylphosphoryl-choline - CAS 1670-26-4 - Calbiochem
  • merck millipore,默克密理博,567735,Sphingosylphosphoryl-choline - CAS 1670-26-4 - Calbiochem

    产品名称:Sphingosylphosphoryl-choline - CAS 1670-26-4 - Calbiochem
    产品型号:567735
    SPC is the deacylated derivative of sphingomyelin known to accumulate in neuropathic Niemann-Pick disease type A.

    merck millipore,默克密理博,567735,Sphingosylphosphoryl-choline - CAS 1670-26-4 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,567735,Sphingosylphosphoryl-choline - CAS 1670-26-4 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₃H₄₉N₂O₅P1670-26-4
    描述
    概述 SPC is the deacylated derivative of sphingomyelin known to accumulate in neuropathic Niemann-Pick disease type A. A potent mitogen that increases intracellular free Ca2+ and free arachidonate through pathways that are only partially PKC-dependent. Stimulates DNA-binding activity of the transcription activator protein AP-1. Rapidly induces tyrosine phosphorylation of focal adhesion kinase (p125FAK) and paxillin and causes a rapid and transient activation of MAP kinase in Swiss/3T3 cells. Also induces a unique reorganization of the actin cytoskeleton.
    产品目录编号 567735
    品牌系列 Calbiochem®
    同义词 SPC, lyso-Sphingomyelin
    参考
    参考 Berger, A., et al. 1995. Proc. Natl. Acad. Sci. USA 92, 5885.
    Dettbarn, C., et al. 1995. Brain Res. 669, 79.
    Seufferlein, T. and Rozengurt, E. 1995. J. Biol. Chem. 270, 24343.
    Seufferlein, T. and Rozengurt, E. 1995. J. Biol. Chem. 270, 24334.
    产品信息
    CAS号 1670-26-4
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₂₃H₄₉N₂O₅P
    化学配方 C₂₃H₄₉N₂O₅P
    Molar Mass 464.6
    可逆 N
    结构配方图像
    生物信息
    主靶 A potent mitogen
    纯度 ≥98% by TLC
    理化信息
    细胞可渗透 N
    溶解度 Chloroform:MeOH (2:1)
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    防潮 Protect from moisture
    无需冷冻 No
    特殊指南 Following initial thaw, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.

    merck millipore,默克密理博,567735,Sphingosylphosphoryl-choline - CAS 1670-26-4 - Calbiochem

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